Naproxen and Intestinal ischaemia - a phase IV clinical study of FDA data

Summary:

Intestinal ischaemia is reported as a side effect among people who take Naproxen (naproxen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ondansetron, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Intestinal ischaemia when taking Naproxen. It is created by eHealthMe based on reports of 68,942 people who have side effects when taking Naproxen from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,033 Naproxen users. Check the latest studies of Naproxen.

What is Intestinal ischaemia?

Intestinal ischaemia (decreased supply of oxygenated blood to the intestines) is found to be associated with 676 drugs and 833 conditions by eHealthMe. Check the latest studies of Intestinal ischaemia.

On Aug, 03, 2026

68,942 people reported to have side effects when taking Naproxen.
Among them, 20 people (0.03%) have Intestinal ischaemia.

Could Naproxen cause Intestinal ischaemia?

Among these 20 people:

How long have people been on Naproxen when they have Intestinal ischaemia? *

What is the gender of people who have Intestinal ischaemia when taking Naproxen? *

female: 73.68 %
male: 26.32 %

What is the age of people who have Intestinal ischaemia when taking Naproxen? *

What are other drugs people take besides Naproxen? *

What are other side effects people have besides Intestinal ischaemia? *

Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 4 people, 20.00%
Nausea (feeling of having an urge to vomit): 4 people, 20.00%
Abdominal Pain: 3 people, 15.00%
Septic Shock (shock due to blood infection): 3 people, 15.00%
Multi-Organ Failure (multisystem organ failure): 3 people, 15.00%
Nausea And Vomiting: 3 people, 15.00%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 15.00%
Fever: 3 people, 15.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 15.00%
Hepatorenal Syndrome (renal failure in patients with advanced chronic liver disease): 2 people, 10.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 20.00%
Small Cell Lung Cancer Extensive Stage (small cell lung cancer that has spread (metastasized) to other regions of the body such as another lobe of the lung or the brain): 3 people, 15.00%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 2 people, 10.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 10.00%
Intervertebral Disc Degeneration (spinal disc degeneration): 2 people, 10.00%
High Blood Pressure: 2 people, 10.00%
Fever: 2 people, 10.00%
Renal Cell Carcinoma (a kidney cancer): 1 person, 5.00%
Neuroendocrine Tumor: 1 person, 5.00%
Escherichia Sepsis (bacterial infection by escherichia coli): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen and have Intestinal ischaemia?

- Check whether Intestinal ischaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naproxen:

Naproxen (72,033 reports)

Browse all side effects of Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal ischaemia:

Intestinal ischaemia (676 drugs)

Browse all the conditions that are associated with Intestinal ischaemia:

Intestinal ischaemia (833 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naproxen (the active ingredients of Naproxen) and Naproxen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.