Niacin and Aphthous stomatitis - a phase IV clinical study of FDA data

Summary:

Aphthous stomatitis is reported as a side effect among people who take Niacin (niacin), especially for people who are female, 60+ old, also take Premarin, and have Osteoarthritis.

The phase IV clinical study analyzes which people have Aphthous stomatitis when taking Niacin. It is created by eHealthMe based on reports of 7,974 people who have side effects when taking Niacin from the FDA, and is updated regularly.

What is Niacin?

Niacin has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 9,008 Niacin users. Check the latest studies of Niacin.

What is Aphthous stomatitis?

Aphthous stomatitis (mouth ulcer) is found to be associated with 432 drugs and 811 conditions by eHealthMe. Check the latest studies of Aphthous stomatitis.

On Jul, 08, 2026

7,974 people reported to have side effects when taking Niacin.
Among them, 12 people (0.15%) have Aphthous stomatitis.

Among these 12 people:

What is the gender of people who have Aphthous stomatitis when taking Niacin? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Aphthous stomatitis when taking Niacin? *

What are other drugs people take besides Niacin? *

Forteo: 6 people, 50.00%
Fosamax: 6 people, 50.00%
Premarin: 6 people, 50.00%
Keflex: 5 people, 41.67%
Alendronate Sodium: 5 people, 41.67%
Vitamins: 5 people, 41.67%
Vioxx: 5 people, 41.67%
Omega-3 Marine Triglycerides: 5 people, 41.67%
Cephalexin: 4 people, 33.33%
Kenalog-10: 3 people, 25.00%

What are other side effects people have besides Aphthous stomatitis? *

Fatigue (feeling of tiredness): 10 people, 83.33%
Back Pain: 9 people, 75.00%
Anaemia (lack of blood): 8 people, 66.67%
Fall: 8 people, 66.67%
Acne (skin problems that cause pimples): 7 people, 58.33%
Colon Adenoma (non cancerous epithelial colon tumour having a glandular origin and structure): 7 people, 58.33%
Muscle Spasms (muscle contraction): 7 people, 58.33%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 50.00%
Neck Pain: 6 people, 50.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 50.00%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 6 people, 50.00%
Osteopenia (a condition where bone mineral density is lower than normal): 6 people, 50.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 50.00%
Acne (skin problems that cause pimples): 3 people, 25.00%
Sinusitis (inflammation of sinus): 2 people, 16.67%
Pain: 2 people, 16.67%
Multiple Myeloma (cancer of the plasma cells): 2 people, 16.67%
Insomnia (sleeplessness): 2 people, 16.67%
Gastric Ulcer (stomach ulcer): 2 people, 16.67%
Allergic Sinusitis: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Niacin and have Aphthous stomatitis?

- Check whether Aphthous stomatitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Niacin:

Niacin (9,008 reports)

Browse all side effects of Niacin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aphthous stomatitis:

Aphthous stomatitis (432 drugs)

Browse all the conditions that are associated with Aphthous stomatitis:

Aphthous stomatitis (811 conditions)

Related publications that referenced our studies

Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .
Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on niacin (the active ingredients of Niacin) and Niacin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.