Nicotinamide and Overdose - a phase IV clinical study of FDA data

Summary:

Overdose is reported as a side effect among people who take Nicotinamide (niacin and niacinamide (vitamin b3)), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Actemra, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Overdose when taking Nicotinamide. It is created by eHealthMe based on reports of 1,954 people who have side effects when taking Nicotinamide from the FDA, and is updated regularly.

What is Nicotinamide?

Nicotinamide has active ingredients of niacin and niacinamide (vitamin b3). eHealthMe is studying from 1,991 Nicotinamide users. Check the latest studies of Nicotinamide.

What is Overdose?

Overdose is found to be associated with 2,218 drugs and 2,472 conditions by eHealthMe. Check the latest studies of Overdose.

On Jul, 14, 2026

1,954 people reported to have side effects when taking Nicotinamide.
Among them, 19 people (0.97%) have Overdose.

Among these 19 people:

How long have people been on Nicotinamide when they have Overdose? *

What is the gender of people who have Overdose when taking Nicotinamide? *

female: 64.29 %
male: 35.71 %

What is the age of people who have Overdose when taking Nicotinamide? *

What are other drugs people take besides Nicotinamide? *

Actemra: 12 people, 63.16%
Folic Acid: 11 people, 57.89%
Prednisone: 11 people, 57.89%
Leflunomide: 11 people, 57.89%
Acetaminophen: 10 people, 52.63%
Azathioprine Sodium: 10 people, 52.63%
Fosamax: 10 people, 52.63%
Humira: 10 people, 52.63%
Pseudoephedrine Hydrochloride: 10 people, 52.63%
Hydroxychloroquine Sulfate: 10 people, 52.63%

What are other side effects people have besides Overdose? *

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 11 people, 57.89%
High Blood Pressure: 11 people, 57.89%
Impaired Healing: 10 people, 52.63%
Depression: 10 people, 52.63%
Diarrhea: 10 people, 52.63%
Maternal Exposure During Pregnancy (use of substance during pregnancy): 10 people, 52.63%
Drug Ineffective: 10 people, 52.63%
Lower Respiratory Tract Infection: 10 people, 52.63%
Joint Pain: 10 people, 52.63%
Duodenal Ulcer Perforation (untreated ulcer can burn through the wall of the stomach): 10 people, 52.63%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 63.16%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 10 people, 52.63%
Psoriasis (immune-mediated disease that affects the skin): 10 people, 52.63%
Migraine (headache): 10 people, 52.63%
Diabetes: 5 people, 26.32%
Pain: 4 people, 21.05%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 4 people, 21.05%
High Blood Cholesterol: 4 people, 21.05%
Herpes Simplex (herpes simplex is a common viral infection): 4 people, 21.05%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 4 people, 21.05%

* Approximation only. Some reports may have incomplete information.

Do you take Nicotinamide and have Overdose?

- Check whether Overdose is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nicotinamide:

Nicotinamide (1,991 reports)

Overdose treatments and more:

Overdose (229,245 reports)

How severe was Overdose and when was it recovered:

Overdose in Nicotinamide

Expand to all the drugs that have ingredients of niacin and niacinamide (vitamin b3):

Overdose and drugs with ingredients of niacin and niacinamide (vitamin b3)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nicotinamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Overdose:

Overdose (2,218 drugs)

Browse all the conditions that are associated with Overdose:

Overdose (2,472 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on niacin and niacinamide (vitamin b3) (the active ingredients of Nicotinamide) and Nicotinamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.