Nifedipine and Quadriparesis - a phase IV clinical study of FDA data

Summary:

Quadriparesis is reported as a side effect among people who take Nifedipine (nifedipine), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Aspirin, and have Gastric ulcer.

The phase IV clinical study analyzes which people have Quadriparesis when taking Nifedipine. It is created by eHealthMe based on reports of 52,610 people who have side effects when taking Nifedipine from the FDA, and is updated regularly.

What is Nifedipine?

Nifedipine has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 53,459 Nifedipine users. Check the latest studies of Nifedipine.

What is Quadriparesis?

Quadriparesis (muscle weakness affecting all four limbs) is found to be associated with 189 drugs and 696 conditions by eHealthMe. Check the latest studies of Quadriparesis.



On Aug, 07, 2026

52,610 people reported to have side effects when taking Nifedipine.
Among them, 12 people (0.02%) have Quadriparesis.

Could Nifedipine cause Quadriparesis?

Among these 12 people:

How long have people been on Nifedipine when they have Quadriparesis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Quadriparesis when taking Nifedipine? *

  • female: 27.27 %
  • male: 72.73 %

What is the age of people who have Quadriparesis when taking Nifedipine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 11.11 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 22.22 %
  • 60+: 66.67 %

What are other drugs people take besides Nifedipine? *

  1. Aspirin: 6 people, 50.00%
  2. Acarbose: 4 people, 33.33%
  3. Etodolac: 4 people, 33.33%
  4. Glimepiride: 4 people, 33.33%
  5. Metformin: 4 people, 33.33%
  6. Lipitor: 3 people, 25.00%
  7. Indapamide: 3 people, 25.00%
  8. Ginkgo Biloba: 3 people, 25.00%
  9. Gabapentin: 3 people, 25.00%
  10. Famotidine: 3 people, 25.00%

What are other side effects people have besides Quadriparesis? *

  1. Swallowing Difficulty: 6 people, 50.00%
  2. Speech Impairment (Adult) (inability to speak (adult)): 6 people, 50.00%
  3. Eosinophilia (eosinophil count in the peripheral blood exceeds): 4 people, 33.33%
  4. Cerebral Infarction (less blood supply to brain resulting tissue damage): 4 people, 33.33%
  5. Hypotension (abnormally low blood pressure): 3 people, 25.00%
  6. Impaired Work Ability: 3 people, 25.00%
  7. Intervertebral Disc Protrusion (spinal disc protrusion): 3 people, 25.00%
  8. Joint Injury: 3 people, 25.00%
  9. Kidney Stones: 3 people, 25.00%
  10. Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 3 people, 25.00%

What are the existing conditions these people have? *

  1. Gastric Ulcer (stomach ulcer): 5 people, 41.67%
  2. Neuralgia (pain in one or more nerves): 4 people, 33.33%
  3. Pain: 3 people, 25.00%
  4. Insomnia (sleeplessness): 3 people, 25.00%
  5. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 25.00%
  6. Faeces Hard: 3 people, 25.00%
  7. Constipation: 3 people, 25.00%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 25.00%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 16.67%
  10. Heart Rate Irregular: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Nifedipine and have Quadriparesis?

- Check whether Quadriparesis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nifedipine:

Quadriparesis treatments and more:

How severe was Quadriparesis and when was it recovered:

Expand to all the drugs that have ingredients of nifedipine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nifedipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Quadriparesis:

Browse all the conditions that are associated with Quadriparesis:


How the study uses the data?

The study uses data from the FDA. It is based on nifedipine (the active ingredients of Nifedipine) and Nifedipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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