Nolvadex and Hepatic failure - a phase IV clinical study of FDA data

Summary:

Hepatic failure is reported as a side effect among people who take Nolvadex (tamoxifen citrate), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Taxotere, and have Cancer pain.

The phase IV clinical study analyzes which people have Hepatic failure when taking Nolvadex. It is created by eHealthMe based on reports of 5,421 people who have side effects when taking Nolvadex from the FDA, and is updated regularly.

What is Nolvadex?

Nolvadex has active ingredients of tamoxifen citrate. It is often used in breast cancer. eHealthMe is studying from 5,506 Nolvadex users. Check the latest studies of Nolvadex.

What is Hepatic failure?

Hepatic failure (liver failure) is found to be associated with 1,541 drugs and 1,892 conditions by eHealthMe. Check the latest studies of Hepatic failure.

On Jul, 12, 2026

5,421 people reported to have side effects when taking Nolvadex.
Among them, 19 people (0.35%) have Hepatic failure.

Among these 19 people:

How long have people been on Nolvadex when they have Hepatic failure? *

What is the gender of people who have Hepatic failure when taking Nolvadex? *

female: 100 %
male: 0.0 %

What is the age of people who have Hepatic failure when taking Nolvadex? *

What are other drugs people take besides Nolvadex? *

What are other side effects people have besides Hepatic failure? *

Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 6 people, 31.58%
Anuria (failure of the kidneys to produce urine): 4 people, 21.05%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 21.05%
Rashes (redness): 3 people, 15.79%
Cancer Pain: 3 people, 15.79%
Osteonecrosis Of Jaw (death of bone of jaw): 3 people, 15.79%
Local Swelling (swelling at the site of some application of substance or injury): 3 people, 15.79%
Neoplasm Malignant (cancer tumour): 3 people, 15.79%
Metastases To Liver (cancer spreads to liver): 3 people, 15.79%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 3 people, 15.79%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 3 people, 15.79%
Cancer Pain: 3 people, 15.79%
Indigestion: 2 people, 10.53%
T-Cell Lymphoma Recurrent (reoccurs a blood cell cancer): 1 person, 5.26%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 5.26%
Pain: 1 person, 5.26%
Histiocytosis Haematophagic: 1 person, 5.26%
Disease Recurrence: 1 person, 5.26%
Congestive Cardiomyopathy (weakening of heart muscle): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Nolvadex and have Hepatic failure?

- Check whether Hepatic failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nolvadex:

Nolvadex (5,506 reports)

Hepatic failure treatments and more:

Hepatic failure (44,058 reports)

Browse all side effects of Nolvadex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic failure:

Hepatic failure (1,541 drugs)

Browse all the conditions that are associated with Hepatic failure:

Hepatic failure (1,892 conditions)

Related publications that referenced our studies

K?rm?z?bekmez H, Yesiltepe Mutlu RG, Dursun F, ??güven ?P, "Tamoxifen-associated hirsutism: an unusual side effect in a 5-year-old girl with McCune-Albright syndrome", Journal of Pediatric Endocrinology and Metabolism, 2015 Sep .
K?rm?z?bekmez H, Yesiltepe Mutlu RG, Dursun F, ??güven ?P, "Tamoxifen-associated hirsutism: an unusual side effect in a 5-year-old girl with McCune-Albright syndrome", Journal of Pediatric Endocrinology and Metabolism, 2015 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on tamoxifen citrate (the active ingredients of Nolvadex) and Nolvadex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.