Oxycontin and Aggression - a phase IV clinical study of FDA data

Summary:

Aggression is reported as a side effect among people who take Oxycontin (oxycodone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Hydrocodone Bitartrate And Acetaminophen, and have Joint pain.

The phase IV clinical study analyzes which people have Aggression when taking Oxycontin. It is created by eHealthMe based on reports of 210,595 people who have side effects when taking Oxycontin from the FDA, and is updated regularly.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,532 Oxycontin users. Check the latest studies of Oxycontin.

What is Aggression?

Aggression is found to be associated with 1,615 drugs and 1,955 conditions by eHealthMe. Check the latest studies of Aggression.

On Nov, 09, 2025

210,595 people reported to have side effects when taking Oxycontin.
Among them, 950 people (0.45%) have Aggression.

Among these 950 people:

* Approximation only. Some reports may have incomplete information.

Do you take Oxycontin and have Aggression?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycontin:

Oxycontin (212,532 reports)

Aggression treatments and more:

Aggression (65,309 reports)

How severe was Aggression and when was it recovered:

Aggression in Oxycontin

Expand to all the drugs that have ingredients of oxycodone hydrochloride:

Aggression and drugs with ingredients of oxycodone hydrochloride (1,273 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Oxycontin side effects:

Browse all side effects of Oxycontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Aggression:

Browse all the drugs that are associated with Aggression:

Aggression (1,615 drugs)

Common conditions associated with Aggression:

Depression: 4,895 reports
Antidepressant therapy: 4,854 reports
Cigarette smoking: 3,113 reports
Attention deficit disorder with hyperactivity (addh): 3,017 reports
Schizophrenia: 2,310 reports
Anxiety: 2,227 reports
Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension: 2,220 reports
Epilepsy: 1,987 reports
Seizure disorder: 1,970 reports
Pain: 1,895 reports

Browse all the conditions that are associated with Aggression:

Aggression (1,955 conditions)

Drugs similar to Oxycontin and Aggression :

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycontin) and Oxycontin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.