Oxycontin and Coma - a phase IV clinical study of FDA data

Summary:

Coma is reported as a side effect among people who take Oxycontin (oxycodone hydrochloride), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Dilaudid, and have Depression.

The phase IV clinical study analyzes which people have Coma when taking Oxycontin. It is created by eHealthMe based on reports of 210,595 people who have side effects when taking Oxycontin from the FDA, and is updated regularly.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,532 Oxycontin users. Check the latest studies of Oxycontin.

What is Coma?

Coma (state of unconsciousness lasting more than six hours) is found to be associated with 2,895 drugs and 3,164 conditions by eHealthMe. Check the latest studies of Coma.

On Oct, 16, 2025

210,595 people reported to have side effects when taking Oxycontin.
Among them, 1,475 people (0.7%) have Coma.

Among these 1,475 people:

How long have people been on Oxycontin when they have Coma? *

What is the gender of people who have Coma when taking Oxycontin? *

female: 44.32 %
male: 55.68 %

What is the age of people who have Coma when taking Oxycontin? *

What are other drugs people take besides Oxycontin? *

Dilaudid: 141 people, 9.56%
Hydrocodone Bitartrate And Acetaminophen: 137 people, 9.29%
Xanax: 116 people, 7.86%
Ms Contin: 113 people, 7.66%
Neurontin: 109 people, 7.39%
Vicodin: 85 people, 5.76%
Percocet: 80 people, 5.42%
Ambien: 66 people, 4.47%
Valium: 66 people, 4.47%
Celebrex: 59 people, 4.00%

What are other side effects people have besides Coma? *

Drug Dependence: 403 people, 27.32%
Overdose: 365 people, 24.75%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 174 people, 11.80%
Depression: 131 people, 8.88%
Memory Loss: 130 people, 8.81%
Multiple Drug Overdose: 119 people, 8.07%
Head Injury: 117 people, 7.93%
Drowsiness: 114 people, 7.73%
Stress And Anxiety: 112 people, 7.59%
Fatigue (feeling of tiredness): 104 people, 7.05%

What are the existing conditions these people have? *

Depression: 47 people, 3.19%
High Blood Pressure: 31 people, 2.10%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 24 people, 1.63%
Insomnia (sleeplessness): 23 people, 1.56%
High Blood Cholesterol: 23 people, 1.56%
Stress And Anxiety: 22 people, 1.49%
Type 2 Diabetes: 18 people, 1.22%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 18 people, 1.22%
Cancer Pain: 18 people, 1.22%
Cluster Headache (one-sided head pain with tearing): 16 people, 1.08%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycontin and have Coma?

- Check whether Coma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycontin:

Oxycontin (212,532 reports)

Coma treatments and more:

Coma (57,420 reports)

Common Oxycontin side effects:

Browse all side effects of Oxycontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Coma:

Browse all the drugs that are associated with Coma:

Coma (2,895 drugs)

Common conditions associated with Coma:

Pain exacerbated: 2,578 reports
Alternative medicine - pain relief: 2,471 reports
Depression aggravated: 1,998 reports
Antidepressant therapy: 1,968 reports
Hypertension: 1,963 reports
Htn: 1,924 reports
Multiple sclerosis aggravated: 1,512 reports
Acupuncture and pain: 1,424 reports
Arthritis - rheumatoid: 1,182 reports
Diabetes mellitus aggravated: 1,167 reports

Browse all the conditions that are associated with Coma:

Coma (3,164 conditions)

Drugs similar to Oxycontin and Coma :

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycontin) and Oxycontin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.