Suboxone and Coma - a phase IV clinical study of FDA data
Summary:
Coma is reported as a side effect among people who take Suboxone (buprenorphine hydrochloride; naloxone hydrochloride), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Oxycontin, and have Drug dependence.
The phase IV clinical study analyzes which people have Coma when taking Suboxone. It is created by eHealthMe based on reports of 28,308 people who have side effects when taking Suboxone from the FDA, and is updated regularly.
What is Suboxone?
Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 31,249 Suboxone users. Check the latest studies of Suboxone.
What is Coma?
Coma (state of unconsciousness lasting more than six hours) is found to be associated with 2,865 drugs and 3,182 conditions by eHealthMe. Check the latest studies of Coma.
On Jan, 30, 2026
28,308 people reported to have side effects when taking Suboxone.
Among them, 107 people (0.38%) have Coma.
Among these 107 people:
How long have people been on Suboxone when they have Coma? *
What is the gender of people who have Coma when taking Suboxone? *
What is the age of people who have Coma when taking Suboxone? *
What are other drugs people take besides Suboxone? *
What are other side effects people have besides Coma? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Suboxone and have Coma?
- Check whether Coma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Suboxone:
- Suboxone (31,249 reports)
Coma treatments and more:
- Coma (57,420 reports)
How severe was Coma and when was it recovered:
Expand to all the drugs that have ingredients of buprenorphine hydrochloride; naloxone hydrochloride:
- Coma and drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride (113 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Suboxone side effects:
- Suboxone side effect: Drug dependence (4,977 reports)
- Suboxone side effect: Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation) (4,036 reports)
- Suboxone side effect: Overdose (2,108 reports)
- Suboxone side effect: Emotional distress (1,570 reports)
- Suboxone side effect: Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect) (1,515 reports)
- Suboxone side effect: Headache (pain in head) (1,415 reports)
- Suboxone side effect: Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother) (1,260 reports)
- Suboxone side effect: Suicidal ideation (990 reports)
- Suboxone side effect: Maternal exposure during pregnancy (use of substance during pregnancy) (948 reports)
- Suboxone side effect: Diarrhea (833 reports)
- Suboxone side effect: Drug ineffective (753 reports)
- Suboxone side effect: Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body) (752 reports)
- Suboxone side effect: Dyspnea (difficult or laboured breathing) (661 reports)
- Suboxone side effect: Back pain (655 reports)
- Suboxone side effect: Loss of consciousness (642 reports)
- Suboxone side effect: Fall (629 reports)
- Suboxone side effect: Drug exposure during pregnancy (585 reports)
- Suboxone side effect: Road traffic accident (565 reports)
- Suboxone side effect: Weight decreased (556 reports)
- Suboxone side effect: Condition (538 reports)
- Suboxone side effect: Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability) (512 reports)
- Suboxone side effect: Pain in extremity (509 reports)
- Suboxone side effect: Oedema peripheral (superficial swelling) (463 reports)
- Suboxone side effect: Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) (458 reports)
- Suboxone side effect: Agitation (state of anxiety or nervous excitement) (451 reports)
- Suboxone side effect: Abortion spontaneous (naturally occurring miscarriage) (405 reports)
- Suboxone side effect: Developmental delay (400 reports)
- Suboxone side effect: Euphoric mood (excessively happy but may become angry or irritable) (392 reports)
- Suboxone side effect: Abdominal pain upper (391 reports)
- Suboxone side effect: Disability (376 reports)
- Suboxone side effect: Dental caries (372 reports)
- Suboxone side effect: Hospitalisation (365 reports)
- Suboxone side effect: Learning disability (difficulty in learning) (357 reports)
- Suboxone side effect: Therapeutic response unexpected (353 reports)
- Suboxone side effect: Muscle spasms (muscle contraction) (351 reports)
- Suboxone side effect: Premature baby (325 reports)
- Suboxone side effect: Panic disorder (311 reports)
- Suboxone side effect: Itching (301 reports)
- Suboxone side effect: Chills (felling of cold) (296 reports)
- Suboxone side effect: Abdominal discomfort (295 reports)
- Suboxone side effect: Dependence (291 reports)
- Suboxone side effect: Confusional state (284 reports)
- Suboxone side effect: Seizures (abnormal excessive or synchronous neuronal activity in the brain) (283 reports)
- Suboxone side effect: Tooth loss (279 reports)
- Suboxone side effect: Adverse event (276 reports)
- Suboxone side effect: Tooth disorder (tooth disease) (274 reports)
- Suboxone side effect: Suicide attempt (269 reports)
- Suboxone side effect: Hypoaesthesia (reduced sense of touch or sensation) (253 reports)
- Suboxone side effect: Stomatitis (inflammation of mucous membrane of mouth) (252 reports)
- Suboxone side effect: Hepatitis c (250 reports)
- Suboxone side effect: Drug detoxification (242 reports)
- Suboxone side effect: Dehydration (dryness resulting from the removal of water) (237 reports)
- Suboxone side effect: Nervousness (225 reports)
- Suboxone side effect: Gait disturbance (224 reports)
- Suboxone side effect: Premature delivery (219 reports)
- Suboxone side effect: Injury (216 reports)
- Suboxone side effect: Heart attack (212 reports)
- Suboxone side effect: Vision blurred (202 reports)
- Suboxone side effect: Crying (200 reports)
- Suboxone side effect: Nasopharyngitis (inflammation of the nasopharynx) (196 reports)
- Suboxone side effect: Muscle aches (muscle pain) (195 reports)
- Suboxone side effect: Mood swings (an extreme or rapid change in mood) (193 reports)
- Suboxone side effect: Toothaches (tooth pain) (176 reports)
- Suboxone side effect: Anger (175 reports)
- Suboxone side effect: Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect) (172 reports)
- Suboxone side effect: Psychomotor hyperactivity (feelings of extreme restlessness) (169 reports)
- Suboxone side effect: Influenza like illness (166 reports)
- Suboxone side effect: Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur) (164 reports)
- Suboxone side effect: Skin - clammy (162 reports)
- Suboxone side effect: Drug screen positive (160 reports)
- Suboxone side effect: Feeling of body temperature change (154 reports)
- Suboxone side effect: Visual impairment (153 reports)
- Suboxone side effect: Peripheral swelling (150 reports)
- Suboxone side effect: Low birth weight baby (145 reports)
- Suboxone side effect: Neck pain (143 reports)
- Suboxone side effect: Swollen tongue (swelling of tongue) (142 reports)
- Suboxone side effect: Hallucination, auditory (perceiving sounds without auditory stimulus) (134 reports)
- Suboxone side effect: Muscle twitching (133 reports)
- Suboxone side effect: Drug hypersensitivity (129 reports)
- Suboxone side effect: General physical health deterioration (weak health status) (126 reports)
- Suboxone side effect: Procedural pain (125 reports)
- Suboxone side effect: Urination - painful (124 reports)
- Suboxone side effect: Restless leg syndrome (a powerful urge to move your legs) (122 reports)
- Suboxone side effect: Oral pain (120 reports)
- Suboxone side effect: Cellulitis (infection under the skin) (118 reports)
- Suboxone side effect: Arthritis (form of joint disorder that involves inflammation of one or more joints) (112 reports)
- Suboxone side effect: Prescribed overdose (111 reports)
- Suboxone side effect: Anaemia (lack of blood) (109 reports)
- Suboxone side effect: Fainting (loss of consciousness and postural tone) (108 reports)
- Suboxone side effect: Feeling cold (106 reports)
- Suboxone side effect: Hallucination, visual (seeing things that aren't there) (103 reports)
- Suboxone side effect: Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves) (101 reports)
Browse all side effects of Suboxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Coma:
- Tramadol (2,322 reports)
- Alprazolam (2,237 reports)
- Diazepam (2,182 reports)
- Morphine (2,005 reports)
- Loraz (1,922 reports)
- Prednisone (1,876 reports)
- Acetaminophen (1,813 reports)
- Baclofen (1,798 reports)
- Aspirin (1,760 reports)
- Metformin (1,747 reports)
- Lyrica (1,731 reports)
- Zopiclone (1,649 reports)
- Furosemide (1,592 reports)
- Oxycontin (1,409 reports)
- Gabapentin (1,329 reports)
- Ibu (1,300 reports)
- Profen (1,299 reports)
- Olanzapine (1,259 reports)
- Clonazepam (1,236 reports)
- Zolpidem (1,229 reports)
- Paracetamol (1,225 reports)
- Mirtazapine (1,191 reports)
- Ativan (1,135 reports)
- Pregabalin (1,126 reports)
- Xanax (1,113 reports)
- Valium (1,104 reports)
- Amlodipine (1,045 reports)
- Sertraline (1,037 reports)
- Cymbalta (1,036 reports)
- Methotrexate (1,014 reports)
- Fluoxetine (1,008 reports)
- Omeprazole (988 reports)
- Pantoprazole (959 reports)
- Lasix (953 reports)
- Seroquel (950 reports)
- Escitalopram (931 reports)
- Zide (890 reports)
- Hydrochlorothiazide (888 reports)
- Morphine sulfate (881 reports)
- Oxazepam (877 reports)
- Oxycodone (873 reports)
- Neurontin (858 reports)
- Humira (839 reports)
- Lamotrigine (814 reports)
- Zyprexa (775 reports)
- Risperdal (772 reports)
- Lantus (771 reports)
- Paroxetine (753 reports)
- Simvastatin (745 reports)
- Fentanyl (686 reports)
- Valproic acid (684 reports)
- Lisinopril (677 reports)
- Prednisolone (671 reports)
- Melatonin (656 reports)
- Carbamazepine (654 reports)
- Duragesic (651 reports)
- Avonex (650 reports)
- Tramadol hydrochloride (649 reports)
- Atenolol (648 reports)
- Imodium (641 reports)
- Risperidone (637 reports)
- Loratadine (636 reports)
- Depakote (628 reports)
- Plavix (618 reports)
- Mycophenolate mofetil (603 reports)
- Coumadin (598 reports)
- Lopurin (592 reports)
- Abilify (579 reports)
- Alcohol (569 reports)
- Lipitor (564 reports)
- Codeine (557 reports)
- Keppra (556 reports)
- Lamictal (553 reports)
- Tylenol (551 reports)
- Heparin (549 reports)
- Humalog (547 reports)
- Ranitidine (544 reports)
- Cellcept (541 reports)
- Tegretol (540 reports)
- Nexium (532 reports)
- Synthroid (530 reports)
- Haldol (527 reports)
- Fosamax (526 reports)
- Ramipril (519 reports)
- Calcium (518 reports)
- Vioxx (510 reports)
- Acidophilus (507 reports)
- Nasonex (501 reports)
- Clozapine (500 reports)
- Celebrex (498 reports)
- Alendronate sodium (490 reports)
- Zoloft (481 reports)
- Acetylsalicylic acid (479 reports)
- Cannabis (474 reports)
- Fish oil (469 reports)
- Hydramine (464 reports)
- Levothyroxine sodium (462 reports)
- Albuterol (460 reports)
- Diphen (457 reports)
- Levetiracetam (445 reports)
- Nitroglycerin (441 reports)
- Quetiapine fumarate (435 reports)
- Hydroxyzine (426 reports)
- Folic acid (425 reports)
- Vitamin c (423 reports)
- Vitamin d (419 reports)
- Norvasc (414 reports)
- Cyclophosphamide (413 reports)
- Dexamethasone (412 reports)
- Enbrel (411 reports)
- Bisoprolol fumarate (407 reports)
- Lansoprazole (402 reports)
- Percocet (400 reports)
- Sulfatrim (395 reports)
- Vitamin b12 (394 reports)
- Venlafaxine hydrochloride (393 reports)
- Valproate sodium (390 reports)
- Duloxetine hydrochloride (386 reports)
- Zocor (385 reports)
- Stromectol (383 reports)
- Prozac (382 reports)
- Ambien (381 reports)
- Bactrim (380 reports)
- Xarelto (377 reports)
- Benadryl (369 reports)
- Eliquis (368 reports)
- Clonidine (366 reports)
- Sennosides (365 reports)
- Ergocalciferol (364 reports)
- Lovenox (363 reports)
- Vicodin (361 reports)
- Tizanidine hydrochloride (359 reports)
- Bifido (358 reports)
- Atarax (357 reports)
- Tranxene (354 reports)
- Propofol (353 reports)
- Mometasone furoate (348 reports)
- Gliclazide (345 reports)
- Dilaudid (343 reports)
- Nortriptyline hydrochloride (340 reports)
- Tysabri (338 reports)
- Fluorouracil (333 reports)
- Zolpidem tartrate (332 reports)
- Citalopram hydrobromide (323 reports)
- Fenofibrate (318 reports)
- Crestor (317 reports)
- Celecoxib (315 reports)
- Cannabis sativa (312 reports)
- Duragesic-100 (311 reports)
- Diovan (304 reports)
- Lactobacillus (302 reports)
- Spironolactone (300 reports)
- Lioresal (295 reports)
- Escitalopram oxalate (290 reports)
- Atorvastatin calcium (288 reports)
- Mycophenolic acid (286 reports)
- Lexapro (285 reports)
- Tacrolimus (284 reports)
- Donepezil (281 reports)
- Senna (279 reports)
- Wellbutrin (278 reports)
- Topiramate (276 reports)
- Metoprolol tartrate (272 reports)
- Sulfamethoxazole (271 reports)
- Metoclopramide (270 reports)
- Claritin (268 reports)
- Dexpanthenol (267 reports)
- Prilosec (265 reports)
- Docetaxel (264 reports)
- Protonix (263 reports)
- Pentoxifylline (262 reports)
- Xyrem (260 reports)
- Loxapine (259 reports)
- Ms contin (258 reports)
- Losartan (257 reports)
- Nicotinamide (256 reports)
- Clopidogrel (255 reports)
- Letrozole (252 reports)
- Carvedilol (251 reports)
- Klonopin (250 reports)
- Insulin (248 reports)
- Prevacid (247 reports)
- Sertraline hydrochloride (245 reports)
- Magnesium (243 reports)
- Solu-medrol (241 reports)
- Etoposide (239 reports)
- Celexa (238 reports)
- Clozaril (235 reports)
- Norfloxacin (232 reports)
- Temaz (231 reports)
- Telmisartan (230 reports)
- Temazepam (229 reports)
- Ginkgo (227 reports)
- Singulair (225 reports)
- Levaquin (224 reports)
- Methylprednisolone (223 reports)
- Sofosbuvir (222 reports)
- Zoledronic (220 reports)
- Zoledronic acid (219 reports)
- Depakene (218 reports)
- Nifedipine (216 reports)
- Creatine (215 reports)
- Glucosamine (212 reports)
- Exemestane (211 reports)
- Hydrocodone bitartrate and acetaminophen (210 reports)
- Dutasteride (208 reports)
- Fluconazole (207 reports)
- Oxaliplatin (205 reports)
- Augmentin (204 reports)
- Tamsulosin (203 reports)
- Sandostatin (201 reports)
- Cordarone (200 reports)
- Rebif (199 reports)
- Irbesartan (198 reports)
- Phenytoin (197 reports)
- Bifidum (196 reports)
- Tamsulosin hydrochloride (193 reports)
- Potassium iodide (192 reports)
- Avandia (190 reports)
- Amlodipine besylate (188 reports)
- Dilantin (187 reports)
- Remeron (186 reports)
- Akineton (185 reports)
- Humulin r (183 reports)
- Sodium bicarbonate (179 reports)
- Pyridoxine (178 reports)
- Acyclovir (177 reports)
- Flexeril (176 reports)
- Atrovent (175 reports)
- Enalapril maleate (174 reports)
- Elavil (173 reports)
- Verapamil hydrochloride (172 reports)
- Codeine sulfate (171 reports)
- Xyzal (170 reports)
- Amaryl (168 reports)
- Rituxan (166 reports)
- Zometa (165 reports)
- Fludara (162 reports)
- Lacosamide (161 reports)
- Ketoprofen (160 reports)
- Fentanyl citrate (159 reports)
- Paclitaxel (158 reports)
- Pentazocine (157 reports)
- Toprol-xl (156 reports)
- Geodon (155 reports)
- Vitamin e (154 reports)
- Methadone hydrochloride (153 reports)
- Potassium (152 reports)
- Xalatan (151 reports)
- Meropenem (149 reports)
- Sandostatin lar (148 reports)
- Anafranil (147 reports)
- Thiamine (146 reports)
- Novolog (144 reports)
- Glipizide (143 reports)
- Atropine (140 reports)
- Liver oil (139 reports)
- Azathioprine (137 reports)
- Actos (136 reports)
- Methotrexate sodium (135 reports)
- Biotin (133 reports)
- Xeloda (132 reports)
- Xeljanz (131 reports)
- Avelox (130 reports)
- Diclofenac sodium (129 reports)
- Norvir (128 reports)
- Sulfamethoxazole and trimethoprim (126 reports)
- Flomax (125 reports)
- Effexor xr (124 reports)
- Norco (123 reports)
- Altace (122 reports)
- Midazolam (121 reports)
- Bupivacaine (120 reports)
- Acetylcysteine (119 reports)
- Propranolol hydrochloride (118 reports)
- Clobazam (117 reports)
- Betaseron (116 reports)
- Arixtra (115 reports)
- Diclofenac (114 reports)
- Allegra (113 reports)
- Colace (112 reports)
- Inulin (111 reports)
- Tecfidera (110 reports)
- Zestril (109 reports)
- Diprivan (108 reports)
- Sinemet (107 reports)
- Leflunomide (106 reports)
- Capecitabine (105 reports)
- Loperamide hydrochloride (104 reports)
- Glimepiride (103 reports)
- Pulmicort (102 reports)
- Pegasys (101 reports)
Browse all the drugs that are associated with Coma:
- Coma (2,865 drugs)
Common conditions associated with Coma:
- Pain exacerbated: 2,578 reports
- Alternative medicine - pain relief: 2,471 reports
- Depression aggravated: 1,998 reports
- Antidepressant therapy: 1,968 reports
- Hypertension: 1,963 reports
- High blood pressure: 1,924 reports
- Multiple sclerosis aggravated: 1,512 reports
- Acupuncture and pain: 1,424 reports
- Arthritis - rheumatoid: 1,182 reports
- Diabetes mellitus aggravated: 1,167 reports
- Diabetes: 1,141 reports
- Suicide attempt: 1,135 reports
- Diabetes mellitus non-insulin-dependent: 1,051 reports
- Epilepsy aggravated: 959 reports
- Seizure disorder: 941 reports
- Schizophrenia: 807 reports
- Anxiety aggravated: 784 reports
- Tension: 778 reports
- Atrial fibrillation aggravated: 758 reports
- Bipolar disorder: 731 reports
- Bipolar: 724 reports
- Glucose test: 704 reports
- Insomnia exacerbated: 631 reports
- Can't sleep: 630 reports
- Asthma: 465 reports
- High cholesterol: 453 reports
- Pain - back: 447 reports
- Exercise-induced asthma: 431 reports
- Parkinson's disease aggravated: 422 reports
- Poisoning deliberate: 415 reports
- Parkinsonism aggravated: 411 reports
- Lipoprotein test: 410 reports
- Osteoporosis: 400 reports
- Thin bones: 383 reports
- Plasma cell myeloma: 376 reports
- Seizure: 350 reports
- Intentional overdose: 340 reports
- Seizure control: 337 reports
- Thrombosis: 335 reports
- Plaque psoriasis: 324 reports
- Sleep disorder: 322 reports
- Convulsion: 320 reports
- Sleep - too much: 319 reports
- Cerebrovascular accident: 318 reports
- Psychotic disorder: 314 reports
- Hiv infection: 299 reports
- Gastrooesophageal reflux disease: 292 reports
- Ill-defined disorder: 283 reports
- Muscle spasticity: 282 reports
- Preventive health care: 280 reports
- Hiv test: 272 reports
- Copd: 265 reports
- Reduce cholesterol: 264 reports
- Hepatitis c: 261 reports
- Hypothyroid: 260 reports
- Crohns disease: 256 reports
- T1d: 245 reports
- Infection: 230 reports
- Drug abuser: 229 reports
- Drug addiction: 228 reports
- Pneumonia: 227 reports
- Hallucinogen abuse: 222 reports
- Neuralgia: 216 reports
- Postherpetic neuralgia: 214 reports
- Bronchopneumonia: 213 reports
- Breast cancer: 207 reports
- Constipation: 203 reports
- Stool softener needs: 202 reports
- Cancer - breast: 200 reports
- Migraine: 198 reports
- Anticoagulant therapy: 197 reports
- Non-small cell lung cancer: 196 reports
- Migraines: 194 reports
- Overdose: 193 reports
- Sedation: 191 reports
- Fibromyalgia: 183 reports
- Headache: 182 reports
- Nausea aggravated: 181 reports
- Major depressive disorder: 180 reports
- Cardiac failure: 179 reports
- Dyslipidaemia: 178 reports
- Drug dependence: 177 reports
- Analgesic therapy: 175 reports
- Joint inflammation: 173 reports
- Non-hodgkin's lymphoma: 170 reports
- Lymphoma - non-hodgkin's: 168 reports
- Colorectal cancer: 167 reports
- Chronic myeloid leukaemia: 161 reports
- Acute lymphocytic leukemia (all): 158 reports
- Kidney transplant: 155 reports
- Dementia alzheimer's type: 154 reports
- Pyrexia: 153 reports
- Parkinson: 147 reports
- Anaesthesia: 141 reports
- Lung neoplasm malignant: 139 reports
- Status epilepticus: 136 reports
- Neuropathy peripheral: 135 reports
- Breast cancer metastatic: 134 reports
- Daytime sleep disorder: 132 reports
- Cardiac disorder: 131 reports
- Muscle spasm: 127 reports
- Glaucoma: 126 reports
- Dementia: 123 reports
- Lewy body dementia: 122 reports
- Closed angle glaucoma: 121 reports
- Herpes zoster: 120 reports
- Urinary tract infection: 118 reports
- Stop smoking: 117 reports
- Alcohol detoxification: 116 reports
- Cystitis aggravated: 115 reports
- Acute myeloid leukaemia aggravated: 113 reports
- Birth control and family planning: 112 reports
- Immunosuppression: 111 reports
- Bone and joint pain: 109 reports
- Sciatic nerve dysfunction: 108 reports
- Schizoaffective disorder: 103 reports
Browse all the conditions that are associated with Coma:
- Coma (3,182 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on buprenorphine hydrochloride; naloxone hydrochloride (the active ingredients of Suboxone) and Suboxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
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