Prednisolone and Tonic convulsion - a phase IV clinical study of FDA data

Summary:

Tonic convulsion is reported as a side effect among people who take Prednisolone (prednisolone), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Methotrexate, and have Epilepsy.

The phase IV clinical study analyzes which people have Tonic convulsion when taking Prednisolone. It is created by eHealthMe based on reports of 211,370 people who have side effects when taking Prednisolone from the FDA, and is updated regularly.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

What is Tonic convulsion?

Tonic convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it) is found to be associated with 163 drugs and 383 conditions by eHealthMe. Check the latest studies of Tonic convulsion.

On Jul, 08, 2026

211,370 people reported to have side effects when taking Prednisolone.
Among them, 62 people (0.03%) have Tonic convulsion.

Could Prednisolone cause Tonic convulsion?

Among these 62 people:

How long have people been on Prednisolone when they have Tonic convulsion? *

What is the gender of people who have Tonic convulsion when taking Prednisolone? *

female: 35.59 %
male: 64.41 %

What is the age of people who have Tonic convulsion when taking Prednisolone? *

What are other drugs people take besides Prednisolone? *

What are other side effects people have besides Tonic convulsion? *

Depressed Level Of Consciousness: 15 people, 24.19%
Posterior Reversible Encephalopathy Syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss): 9 people, 14.52%
Thrombocytopenia (decrease of platelets in blood): 9 people, 14.52%
Loss Of Consciousness: 8 people, 12.90%
Cerebral Haemorrhage (bleeding within the brain): 8 people, 12.90%
Fever: 7 people, 11.29%
High Blood Pressure: 7 people, 11.29%
Erythema Multiforme (a type of hypersensitivity reaction): 7 people, 11.29%
Agitation (state of anxiety or nervous excitement): 6 people, 9.68%
Hepatic Function Abnormal: 6 people, 9.68%

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 8 people, 12.90%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 8 people, 12.90%
Burkitt Lymphoma (cancer of the lymphatic system): 7 people, 11.29%
Erythema Multiforme (a type of hypersensitivity reaction): 7 people, 11.29%
Nausea And Vomiting: 5 people, 8.06%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 6.45%
Constipation: 4 people, 6.45%
Diabetes: 4 people, 6.45%
Myoclonic Epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs): 4 people, 6.45%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisolone and have Tonic convulsion?

- Check whether Tonic convulsion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prednisolone:

Prednisolone (212,675 reports)

Browse all side effects of Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tonic convulsion:

Tonic convulsion (163 drugs)

Browse all the conditions that are associated with Tonic convulsion:

Tonic convulsion (383 conditions)

Related publications that referenced our studies

Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .
Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on prednisolone (the active ingredients of Prednisolone) and Prednisolone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.