Proamatine and Thrombocytopenia - a phase IV clinical study of FDA data

Summary:

Thrombocytopenia is reported as a side effect among people who take Proamatine (midodrine hydrochloride), especially for people who are female, 50-59 old, also take Plavix, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Thrombocytopenia when taking Proamatine. It is created by eHealthMe based on reports of 946 people who have side effects when taking Proamatine from the FDA, and is updated regularly.

What is Proamatine?

Proamatine has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 968 Proamatine users. Check the latest studies of Proamatine.

What is Thrombocytopenia?

Thrombocytopenia (decrease of platelets in blood) is found to be associated with 2,791 drugs and 4,870 conditions by eHealthMe. Check the latest studies of Thrombocytopenia.

On Jul, 17, 2026

946 people reported to have side effects when taking Proamatine.
Among them, 45 people (4.76%) have Thrombocytopenia.

Could Proamatine cause Thrombocytopenia?

Among these 45 people:

What is the gender of people who have Thrombocytopenia when taking Proamatine? *

female: 53.33 %
male: 46.67 %

What is the age of people who have Thrombocytopenia when taking Proamatine? *

What are other drugs people take besides Proamatine? *

Plavix: 28 people, 62.22%
Lasix: 26 people, 57.78%
Valium: 24 people, 53.33%
Tylenol W/ Codeine No. 3: 23 people, 51.11%
Nitroglycerin: 21 people, 46.67%
Digoxin: 21 people, 46.67%
Oxycontin: 20 people, 44.44%
Decadron: 19 people, 42.22%
Ms Contin: 18 people, 40.00%
Ativan: 18 people, 40.00%

What are other side effects people have besides Thrombocytopenia? *

Cardiac Failure Congestive: 26 people, 57.78%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 24 people, 53.33%
Septic Shock (shock due to blood infection): 24 people, 53.33%
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 22 people, 48.89%
Pleural Effusion (water on the lungs): 20 people, 44.44%
Chronic Renal Failure (kidney failure): 20 people, 44.44%
Cardiac Disorder: 19 people, 42.22%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 19 people, 42.22%
Swallowing Difficulty: 19 people, 42.22%
Bleeding Disorders: 19 people, 42.22%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 20 people, 44.44%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 17 people, 37.78%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 12 people, 26.67%
Pain: 4 people, 8.89%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 6.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 4.44%
Constipation: 2 people, 4.44%
Fever: 2 people, 4.44%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 4.44%
Mucosal Inflammation (infection of mucous membrane): 2 people, 4.44%

* Approximation only. Some reports may have incomplete information.

Do you take Proamatine and have Thrombocytopenia?

- Check whether Thrombocytopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Proamatine:

Proamatine (968 reports)

Thrombocytopenia treatments and more:

Thrombocytopenia (285,083 reports)

Browse all side effects of Proamatine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thrombocytopenia:

Thrombocytopenia (2,791 drugs)

Browse all the conditions that are associated with Thrombocytopenia:

Thrombocytopenia (4,870 conditions)

Related publications that referenced our studies

YavasogluI, I., TurgutkayaII, A., & BolamanIII, Z., "Chlorella-induced thrombocytopenia", DATA, 2018 Jan .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Onder H, Arsava EM, Arat A, Topcuoglu MA, "Acute middle cerebral artery occlusion treated by thrombectomy in a patient with myelodysplastic syndrome and severe thrombocytopenia", Journal of vascular and interventional neurology, 2015 Jan .
YavasogluI, I., TurgutkayaII, A., & BolamanIII, Z., "Chlorella-induced thrombocytopenia", DATA, 2018 Jan .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Onder H, Arsava EM, Arat A, Topcuoglu MA, "Acute middle cerebral artery occlusion treated by thrombectomy in a patient with myelodysplastic syndrome and severe thrombocytopenia", Journal of vascular and interventional neurology, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on midodrine hydrochloride (the active ingredients of Proamatine) and Proamatine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.