Provigil and Sleep apnea syndrome - a phase IV clinical study of FDA data
Summary:
Sleep apnea syndrome is reported as a side effect among people who take Provigil (modafinil), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Xyrem, and have Cataplexy.
The phase IV clinical study analyzes which people have Sleep apnea syndrome when taking Provigil. It is created by eHealthMe based on reports of 23,659 people who have side effects when taking Provigil from the FDA, and is updated regularly.
What is Provigil?
Provigil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 25,230 Provigil users. Check the latest studies of Provigil.
What is Sleep apnea syndrome?
Sleep apnea syndrome is found to be associated with 1,534 drugs and 1,373 conditions by eHealthMe. Check the latest studies of Sleep apnea syndrome.
23,659 people reported to have side effects when taking Provigil.
Among them, 620 people (2.62%) have Sleep apnea syndrome.

Among these 620 people:
How long have people been on Provigil when they have Sleep apnea syndrome? *
What is the gender of people who have Sleep apnea syndrome when taking Provigil? *
What is the age of people who have Sleep apnea syndrome when taking Provigil? *
What are other drugs people take besides Provigil? *
What are other side effects people have besides Sleep apnea syndrome? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Provigil and have Sleep apnea syndrome?
- Check whether Sleep apnea syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Provigil:
- Provigil (25,230 reports)
Sleep apnea syndrome treatments and more:
- Sleep apnea syndrome (31,666 reports)
How severe was Sleep apnea syndrome and when was it recovered:
Expand to all the drugs that have ingredients of modafinil:
- Sleep apnea syndrome and drugs with ingredients of modafinil (1,242 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Provigil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Sleep apnea syndrome:
- Sleep apnea syndrome (1,534 drugs)
Browse all the conditions that are associated with Sleep apnea syndrome:
- Sleep apnea syndrome (1,373 conditions)
Related publications that referenced our studies
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on modafinil (the active ingredients of Provigil) and Provigil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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