Seroquel and Liver function test abnormal - a phase IV clinical study of FDA data

Summary:

Liver function test abnormal is reported as a side effect among people who take Seroquel (quetiapine fumarate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lexapro, and have Pain.

The phase IV clinical study analyzes which people have Liver function test abnormal when taking Seroquel. It is created by eHealthMe based on reports of 113,615 people who have side effects when taking Seroquel from the FDA, and is updated regularly.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,276 Seroquel users. Check the latest studies of Seroquel.

What is Liver function test abnormal?

Liver function test abnormal is found to be associated with 1,549 drugs and 1,943 conditions by eHealthMe. Check the latest studies of Liver function test abnormal.

On Aug, 15, 2025

113,615 people reported to have side effects when taking Seroquel.
Among them, 356 people (0.31%) have Liver function test abnormal.

Could Seroquel cause Liver function test abnormal?

Among these 356 people:

How long have people been on Seroquel when they have Liver function test abnormal? *

What is the gender of people who have Liver function test abnormal when taking Seroquel? *

female: 58.21 %
male: 41.79 %

What is the age of people who have Liver function test abnormal when taking Seroquel? *

What are other drugs people take besides Seroquel? *

What are other side effects people have besides Liver function test abnormal? *

Stress And Anxiety: 42 people, 11.80%
Hepatic Steatosis (fatty liver disease): 42 people, 11.80%
Headache (pain in head): 40 people, 11.24%
Fatigue (feeling of tiredness): 39 people, 10.96%
High Blood Cholesterol: 39 people, 10.96%
Malaise (a feeling of general discomfort or uneasiness): 35 people, 9.83%
Pain: 35 people, 9.83%
Chest Pain: 35 people, 9.83%
Pain In Extremity: 34 people, 9.55%
Type 2 Diabetes: 34 people, 9.55%

What are the existing conditions these people have? *

Pain: 34 people, 9.55%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 29 people, 8.15%
Sleep Disorder: 24 people, 6.74%
Stress And Anxiety: 19 people, 5.34%
Psychotic Disorder: 18 people, 5.06%
Prostate Cancer: 16 people, 4.49%
Bone Density Abnormal: 15 people, 4.21%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 13 people, 3.65%
High Blood Pressure: 12 people, 3.37%
Thyroid Diseases: 10 people, 2.81%

* Approximation only. Some reports may have incomplete information.

Do you take Seroquel and have Liver function test abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Seroquel:

Seroquel (120,276 reports)

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Liver function test abnormal:

Browse all the drugs that are associated with Liver function test abnormal:

Liver function test abnormal (1,549 drugs)

Common conditions associated with Liver function test abnormal:

Ra: 3,254 reports
Ms: 1,865 reports
Hypertension: 1,439 reports
Blood pressure - high: 1,423 reports
Hyperlipidemia: 1,376 reports
Lipoprotein test: 1,344 reports
Pain: 1,285 reports
Primary pulmonary hypertension: 1,264 reports
Antidepressant therapy: 1,173 reports
Reduce cholesterol: 1,162 reports

Browse all the conditions that are associated with Liver function test abnormal:

Liver function test abnormal (1,943 conditions)

Drugs similar to Seroquel and Liver function test abnormal :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on quetiapine fumarate (the active ingredients of Seroquel) and Seroquel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.