Simcor and Syncope - a phase IV clinical study of FDA data

Summary:

Syncope is reported as a side effect among people who take Simcor (niacin; simvastatin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have High density lipoprotein decreased.

The phase IV clinical study analyzes which people have Syncope when taking Simcor. It is created by eHealthMe based on reports of 11,438 people who have side effects when taking Simcor from the FDA, and is updated regularly.

What is Simcor?

Simcor has active ingredients of niacin; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 11,604 Simcor users. Check the latest studies of Simcor.

What is Syncope?

Syncope (loss of consciousness with an inability to maintain postural tone) is found to be associated with 3,470 drugs and 3,504 conditions by eHealthMe. Check the latest studies of Syncope.

On Jan, 30, 2026

11,438 people reported to have side effects when taking Simcor.
Among them, 33 people (0.29%) have Syncope.

Among these 33 people:

How long have people been on Simcor when they have Syncope? *

What is the gender of people who have Syncope when taking Simcor? *

female: 39.29 %
male: 60.71 %

What is the age of people who have Syncope when taking Simcor? *

What are other drugs people take besides Simcor? *

What are other side effects people have besides Syncope? *

Skin Blushing/flushing (a sudden reddening of the face, neck): 11 people, 33.33%
Head Injury: 6 people, 18.18%
Loss Of Consciousness: 6 people, 18.18%
Skin Burning Sensation: 6 people, 18.18%
Hypotension (abnormally low blood pressure): 5 people, 15.15%
Weakness: 4 people, 12.12%
Eating Disorder: 4 people, 12.12%
Dizziness: 4 people, 12.12%
Rashes (redness): 4 people, 12.12%
Feeling Hot: 4 people, 12.12%

What are the existing conditions these people have? *

High Density Lipoprotein Decreased: 5 people, 15.15%
Insomnia (sleeplessness): 4 people, 12.12%
High Blood Pressure: 4 people, 12.12%
Low Density Lipoprotein Increased (cholesterol increased in blood): 3 people, 9.09%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 6.06%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 1 person, 3.03%
Skin Blushing/flushing (a sudden reddening of the face, neck): 1 person, 3.03%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 3.03%
Hypersensitivity: 1 person, 3.03%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Simcor and have Syncope?

- Check whether Syncope is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simcor:

Simcor (11,604 reports)

Syncope treatments and more:

Syncope (131,320 reports)

Browse all side effects of Simcor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Syncope:

Syncope (3,470 drugs)

Browse all the conditions that are associated with Syncope:

Syncope (3,504 conditions)

Drugs similar to Simcor and Syncope :

Related publications that referenced our studies

Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .
Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on niacin; simvastatin (the active ingredients of Simcor) and Simcor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.