Simvastatin and Waxy casts - a phase IV clinical study of FDA data

Summary:

Waxy casts is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, also take Tegsedi, and have Hereditary neuropathic amyloidosis.

The phase IV clinical study analyzes which people have Waxy casts when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,956 Simvastatin users. Check the latest studies of Simvastatin.

What is Waxy casts?

Waxy casts is found to be associated with 233 drugs and 367 conditions by eHealthMe. Check the latest studies of Waxy casts.

On Oct, 05, 2025

249,370 people reported to have side effects when taking Simvastatin.
Among them, 23 people (0.01%) have Waxy casts.

Among these 23 people:

What is the gender of people who have Waxy casts when taking Simvastatin? *

female: 65.22 %
male: 34.78 %

What is the age of people who have Waxy casts when taking Simvastatin? *

What are other drugs people take besides Simvastatin? *

What are other side effects people have besides Waxy casts? *

Glomerular Filtration Rate Decreased: 12 people, 52.17%
Bacterial Test Positive: 11 people, 47.83%
Weakness: 10 people, 43.48%
White Blood Cells Urine Positive: 10 people, 43.48%
Blood Creatinine Increased: 9 people, 39.13%
Urine Protein/creatinine Ratio Increased: 9 people, 39.13%
Urine Leukocyte Esterase Positive: 7 people, 30.43%
Urine Abnormality: 7 people, 30.43%
Protein Urine Present: 7 people, 30.43%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 30.43%

What are the existing conditions these people have? *

Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 10 people, 43.48%
Osteoporosis (bones weak and more likely to break): 3 people, 13.04%
Diabetes: 3 people, 13.04%
Cardiac Failure Congestive: 3 people, 13.04%
Sedation: 2 people, 8.70%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 2 people, 8.70%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 8.70%
Prostate Cancer: 1 person, 4.35%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Waxy casts?

- Check whether Waxy casts is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,956 reports)

Waxy casts treatments and more:

Waxy casts (855 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Waxy casts:

Waxy casts (233 drugs)

Browse all the conditions that are associated with Waxy casts:

Waxy casts (367 conditions)

Drugs similar to Simvastatin and Waxy casts :

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.