Thorazine and Extrapyramidal disorder - a phase IV clinical study of FDA data

Summary:

Extrapyramidal disorder is reported as a side effect among people who take Thorazine (chlorpromazine hydrochloride), especially for people who are male, 30-39 old, have been taking the drug for 1 - 2 years also take Seroquel, and have Psychotic disorder.

The phase IV clinical study analyzes which people have Extrapyramidal disorder when taking Thorazine. It is created by eHealthMe based on reports of 3,071 people who have side effects when taking Thorazine from the FDA, and is updated regularly.

What is Thorazine?

Thorazine has active ingredients of chlorpromazine hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 3,237 Thorazine users. Check the latest studies of Thorazine.

What is Extrapyramidal disorder?

Extrapyramidal disorder (involuntary muscle spasms in the face and neck) is found to be associated with 813 drugs and 960 conditions by eHealthMe. Check the latest studies of Extrapyramidal disorder.

On Jul, 30, 2026

3,071 people reported to have side effects when taking Thorazine.
Among them, 41 people (1.34%) have Extrapyramidal disorder.

Could Thorazine cause Extrapyramidal disorder?

Among these 41 people:

How long have people been on Thorazine when they have Extrapyramidal disorder? *

What is the gender of people who have Extrapyramidal disorder when taking Thorazine? *

female: 42.5 %
male: 57.5 %

What is the age of people who have Extrapyramidal disorder when taking Thorazine? *

What are other drugs people take besides Thorazine? *

What are other side effects people have besides Extrapyramidal disorder? *

Tardive Dyskinesia (a disorder that involves involuntary movements): 25 people, 60.98%
High Blood Cholesterol: 19 people, 46.34%
Diabetes: 17 people, 41.46%
Weight Loss: 14 people, 34.15%
Tremor (trembling or shaking movements in one or more parts of your body): 13 people, 31.71%
Type 2 Diabetes: 11 people, 26.83%
High Blood Pressure: 10 people, 24.39%
Dizziness: 9 people, 21.95%
Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 8 people, 19.51%
Pancreatitis (inflammation of pancreas): 8 people, 19.51%

What are the existing conditions these people have? *

Psychotic Disorder: 8 people, 19.51%
Stress And Anxiety: 6 people, 14.63%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 6 people, 14.63%
Depression: 6 people, 14.63%
Sleep Disorder: 6 people, 14.63%
Indigestion: 3 people, 7.32%
Chest Pain: 3 people, 7.32%
Hallucination, Auditory (perceiving sounds without auditory stimulus): 3 people, 7.32%
Agitation (state of anxiety or nervous excitement): 3 people, 7.32%
Pain: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Thorazine and have Extrapyramidal disorder?

- Check whether Extrapyramidal disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Thorazine:

Thorazine (3,237 reports)

Browse all side effects of Thorazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Extrapyramidal disorder:

Extrapyramidal disorder (813 drugs)

Browse all the conditions that are associated with Extrapyramidal disorder:

Extrapyramidal disorder (960 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorpromazine hydrochloride (the active ingredients of Thorazine) and Thorazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.