Urocit-k and Major depression - a phase IV clinical study of FDA data

Summary:

Major depression is reported as a side effect among people who take Urocit-k (potassium citrate), especially for people who are female, 50-59 old, also take Ibuprofen, and have Breast cancer.

The phase IV clinical study analyzes which people have Major depression when taking Urocit-k. It is created by eHealthMe based on reports of 648 people who have side effects when taking Urocit-k from the FDA, and is updated regularly.

What is Urocit-k?

Urocit-k has active ingredients of potassium citrate. It is often used in kidney stones. eHealthMe is studying from 708 Urocit-k users. Check the latest studies of Urocit-k.

What is Major depression?

Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings) is found to be associated with 804 drugs and 1,475 conditions by eHealthMe. Check the latest studies of Major depression.

On Jul, 05, 2026

648 people reported to have side effects when taking Urocit-k.
Among them, 17 people (2.62%) have Major depression.

Among these 17 people:

What is the gender of people who have Major depression when taking Urocit-k? *

female: 100 %
male: 0.0 %

What is the age of people who have Major depression when taking Urocit-k? *

What are other drugs people take besides Urocit-k? *

What are other side effects people have besides Major depression? *

Hypomania (a mild form of mania, marked by elation and hyperactivity): 17 people, 100.00%
Femur Fracture: 17 people, 100.00%
Flatulence (flatus expelled through the anus): 17 people, 100.00%
Foot Deformity (functional disability of foot): 17 people, 100.00%
Gastrointestinal Inflammation (inflammation of stomach and intestine): 17 people, 100.00%
Genital Herpes (herpes infection of genital): 17 people, 100.00%
Glossitis (infection of tongue with soreness): 17 people, 100.00%
Groin Pain: 17 people, 100.00%
Haemolytic Anaemia (anaemia due to haemolysis): 17 people, 100.00%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 17 people, 100.00%

What are the existing conditions these people have? *

Breast Cancer: 8 people, 47.06%
Osteoporosis (bones weak and more likely to break): 4 people, 23.53%
Multiple Myeloma (cancer of the plasma cells): 4 people, 23.53%
Metastases To Bone (cancer spreads to bone): 4 people, 23.53%
Sleep Disorder: 1 person, 5.88%
Nervousness: 1 person, 5.88%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 5.88%
High Blood Pressure: 1 person, 5.88%
Arrhythmias (irregular heartbeat): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Urocit-k and have Major depression?

- Check whether Major depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Urocit-k:

Urocit-k (708 reports)

Major depression treatments and more:

Major depression (44,979 reports)

Browse all side effects of Urocit-k:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Major depression:

Major depression (804 drugs)

Browse all the conditions that are associated with Major depression:

Major depression (1,475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on potassium citrate (the active ingredients of Urocit-k) and Urocit-k (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.