Vitamin c and Cataplexy - a phase IV clinical study of FDA data
Summary:
Cataplexy is reported as a side effect among people who take Vitamin c (l-ascorbic acid), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Xyrem, and have Narcolepsy.
The phase IV clinical study analyzes which people have Cataplexy when taking Vitamin c. It is created by eHealthMe based on reports of 89,802 people who have side effects when taking Vitamin c from the FDA, and is updated regularly.
What is Vitamin c?
Vitamin c has active ingredients of l-ascorbic acid. It is often used in immune response. eHealthMe is studying from 92,472 Vitamin c users. Check the latest studies of Vitamin c.
What is Cataplexy?
Cataplexy (loss of muscle tone accompanied by full conscious awareness) is found to be associated with 293 drugs and 255 conditions by eHealthMe. Check the latest studies of Cataplexy.
89,802 people reported to have side effects when taking Vitamin c.
Among them, 39 people (0.04%) have Cataplexy.

Among these 39 people:
How long have people been on Vitamin c when they have Cataplexy? *
- < 1 month: 0.0 %
- 1 - 6 months: 33.33 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 33.33 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 33.33 %
What is the gender of people who have Cataplexy when taking Vitamin c? *
- female: 64.1 %
- male: 35.9 %
What is the age of people who have Cataplexy when taking Vitamin c? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 5 %
- 20-29: 10 %
- 30-39: 5 %
- 40-49: 10 %
- 50-59: 15 %
- 60+: 55 %
What are other drugs people take besides Vitamin c? *
- Xyrem: 35 people, 89.74%
- Vitamin D3: 13 people, 33.33%
- Proair Hfa: 12 people, 30.77%
- Vitamin B12: 11 people, 28.21%
- Adderall: 10 people, 25.64%
- Vitamin D: 9 people, 23.08%
- Lipitor: 8 people, 20.51%
- Coenzyme Q10: 7 people, 17.95%
- Cymbalta: 7 people, 17.95%
- Provigil: 6 people, 15.38%
What are other side effects people have besides Cataplexy? *
- Stress And Anxiety: 9 people, 23.08%
- Insomnia (sleeplessness): 6 people, 15.38%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 15.38%
- Nightmares (unpleasant dreams): 5 people, 12.82%
- Drug Ineffective: 4 people, 10.26%
- Mood Swings (an extreme or rapid change in mood): 3 people, 7.69%
- Pain: 3 people, 7.69%
- Emotional Disorder: 3 people, 7.69%
- Crying: 3 people, 7.69%
- Hot Flush (sudden feelings of heat): 3 people, 7.69%
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 39 people, 100.00%
- Osteomyelitis (infection of bone): 3 people, 7.69%
- Cellulitis (infection under the skin): 3 people, 7.69%
- Cuts And Puncture Wounds: 2 people, 5.13%
- Sleep Disorder: 1 person, 2.56%
- Depression: 1 person, 2.56%
- Anaemia (lack of blood): 1 person, 2.56%
- Cardiac Failure Congestive: 1 person, 2.56%
- Chest Pain: 1 person, 2.56%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 2.56%
* Approximation only. Some reports may have incomplete information.
Do you take Vitamin c and have Cataplexy?
- Check whether Cataplexy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Vitamin c:
- Vitamin c (92,472 reports)
Cataplexy treatments and more:
- Cataplexy (41,577 reports)
How severe was Cataplexy and when was it recovered:
Expand to all the drugs that have ingredients of l-ascorbic acid:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vitamin c:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Cataplexy:
- Cataplexy (293 drugs)
Browse all the conditions that are associated with Cataplexy:
- Cataplexy (255 conditions)
Related publications that referenced our studies
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on l-ascorbic acid (the active ingredients of Vitamin c) and Vitamin c (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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