Vitamin e and Hip joint replacement - a phase IV clinical study of FDA data

Summary:

Hip joint replacement is reported as a side effect among people who take Vitamin e (tocopherols and tocotrienols), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Fosamax, and have Psoriasis.

The phase IV clinical study analyzes which people have Hip joint replacement when taking Vitamin e. It is created by eHealthMe based on reports of 41,364 people who have side effects when taking Vitamin e from the FDA, and is updated regularly.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.

What is Hip joint replacement?

Hip joint replacement is found to be associated with 857 drugs and 1,062 conditions by eHealthMe. Check the latest studies of Hip joint replacement.

On Aug, 09, 2026

41,364 people reported to have side effects when taking Vitamin e.
Among them, 86 people (0.21%) have Hip joint replacement.

Could Vitamin e cause Hip joint replacement?

Among these 86 people:

How long have people been on Vitamin e when they have Hip joint replacement? *

What is the gender of people who have Hip joint replacement when taking Vitamin e? *

female: 87.5 %
male: 12.5 %

What is the age of people who have Hip joint replacement when taking Vitamin e? *

What are other drugs people take besides Vitamin e? *

What are other side effects people have besides Hip joint replacement? *

Sinusitis (inflammation of sinus): 26 people, 30.23%
Pain: 25 people, 29.07%
Weight Increased: 25 people, 29.07%
Fatigue (feeling of tiredness): 24 people, 27.91%
Rashes (redness): 22 people, 25.58%
Drug Ineffective: 21 people, 24.42%
Joint Pain: 21 people, 24.42%
Hair Loss: 20 people, 23.26%
Itching: 19 people, 22.09%
Impaired Healing: 19 people, 22.09%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 20 people, 23.26%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 19 people, 22.09%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 18 people, 20.93%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 18 people, 20.93%
Ankylosing Spondylitis (type of arthritis affecting the spine): 17 people, 19.77%
Osteoporosis (bones weak and more likely to break): 15 people, 17.44%
Pain: 15 people, 17.44%
High Blood Cholesterol: 10 people, 11.63%
High Blood Pressure: 9 people, 10.47%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 10.47%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin e and have Hip joint replacement?

- Check whether Hip joint replacement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamin e:

Vitamin e (42,279 reports)

Browse all side effects of Vitamin e:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hip joint replacement:

Hip joint replacement (857 drugs)

Browse all the conditions that are associated with Hip joint replacement:

Hip joint replacement (1,062 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tocopherols and tocotrienols (the active ingredients of Vitamin e) and Vitamin e (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.