Xywav and Therapeutic response unexpected - a phase IV clinical study of FDA data

Summary:

Therapeutic response unexpected is reported as a side effect among people who take Xywav (calcium oxybate; magnesium oxybate; potassium oxybate; sodium oxybate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Adderall, and have Drowsiness.

The phase IV clinical study analyzes which people have Therapeutic response unexpected when taking Xywav. It is created by eHealthMe based on reports of 7,111 people who have side effects when taking Xywav from the FDA, and is updated regularly.

What is Xywav?

Xywav has active ingredients of calcium oxybate; magnesium oxybate; potassium oxybate; sodium oxybate. eHealthMe is studying from 7,134 Xywav users. Check the latest studies of Xywav.

What is Therapeutic response unexpected?

Therapeutic response unexpected is found to be associated with 1,418 drugs and 1,554 conditions by eHealthMe. Check the latest studies of Therapeutic response unexpected.

On Jul, 19, 2026

7,111 people reported to have side effects when taking Xywav.
Among them, 45 people (0.63%) have Therapeutic response unexpected.

Could Xywav cause Therapeutic response unexpected?

Among these 45 people:

How long have people been on Xywav when they have Therapeutic response unexpected? *

What is the gender of people who have Therapeutic response unexpected when taking Xywav? *

female: 62.22 %
male: 37.78 %

What is the age of people who have Therapeutic response unexpected when taking Xywav? *

What are other drugs people take besides Xywav? *

What are other side effects people have besides Therapeutic response unexpected? *

Nausea (feeling of having an urge to vomit): 13 people, 28.89%
Dizziness: 9 people, 20.00%
Nasopharyngitis (inflammation of the nasopharynx): 8 people, 17.78%
Feeling Abnormal: 8 people, 17.78%
Weight Decreased: 7 people, 15.56%
Dyspnea (difficult or laboured breathing): 7 people, 15.56%
Drowsiness: 6 people, 13.33%
Rashes (redness): 5 people, 11.11%
Stress And Anxiety: 5 people, 11.11%
Hyperhidrosis (abnormally increased sweating): 5 people, 11.11%

What are the existing conditions these people have? *

Drowsiness: 37 people, 82.22%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 32 people, 71.11%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 26 people, 57.78%
Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 4.44%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 4.44%
Seasonal Allergy (allergic condition due to certain season): 2 people, 4.44%
Rickets (softening of bones): 2 people, 4.44%
Neurodermatitis (a skin disorder characterized by long lasting itching and scratching): 2 people, 4.44%
Migraine (headache): 2 people, 4.44%
Asthma: 2 people, 4.44%

* Approximation only. Some reports may have incomplete information.

Do you take Xywav and have Therapeutic response unexpected?

- Check whether Therapeutic response unexpected is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xywav:

Xywav (7,134 reports)

Therapeutic response unexpected treatments and more:

Therapeutic response unexpected (48,126 reports)

How severe was Therapeutic response unexpected and when was it recovered:

Therapeutic response unexpected in Xywav

Expand to all the drugs that have ingredients of calcium oxybate; magnesium oxybate; potassium oxybate; sodium oxybate:

Therapeutic response unexpected and drugs with ingredients of calcium oxybate; magnesium oxybate; potassium oxybate; sodium oxybate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xywav:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Therapeutic response unexpected:

Therapeutic response unexpected (1,419 drugs)

Browse all the conditions that are associated with Therapeutic response unexpected:

Therapeutic response unexpected (1,554 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on calcium oxybate; magnesium oxybate; potassium oxybate; sodium oxybate (the active ingredients of Xywav) and Xywav (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.