Zyrtec and Lupus vulgaris - a phase IV clinical study of FDA data

Summary:

Lupus vulgaris is reported as a side effect among people who take Zyrtec (cetirizine hydrochloride), especially for people who are female, 40-49 old, also take Stelara, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Lupus vulgaris when taking Zyrtec. It is created by eHealthMe based on reports of 109,528 people who have side effects when taking Zyrtec from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,620 Zyrtec users. Check the latest studies of Zyrtec.

What is Lupus vulgaris?

Lupus vulgaris (a chronic inflammatory autoimmune disorder that may caused by the mycobacterium tuberculosis) is found to be associated with 138 drugs and 17 conditions by eHealthMe. Check the latest studies of Lupus vulgaris.



On Jul, 31, 2026

109,528 people reported to have side effects when taking Zyrtec.
Among them, 34 people (0.03%) have Lupus vulgaris.

Could Zyrtec cause Lupus vulgaris?

Among these 34 people:

What is the gender of people who have Lupus vulgaris when taking Zyrtec? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Lupus vulgaris when taking Zyrtec? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 90.48 %
  • 50-59: 9.52 %
  • 60+: 0.0 %

What are other drugs people take besides Zyrtec? *

  1. Kevzara: 33 people, 97.06%
  2. Sulfasalazine: 33 people, 97.06%
  3. Actemra: 33 people, 97.06%
  4. Calcium: 33 people, 97.06%
  5. Cimzia: 33 people, 97.06%
  6. Cosentyx: 33 people, 97.06%
  7. Enbrel: 33 people, 97.06%
  8. Erelzi: 33 people, 97.06%
  9. Orencia: 33 people, 97.06%
  10. Stelara: 33 people, 97.06%

What are other side effects people have besides Lupus vulgaris? *

  1. Hair Loss: 34 people, 100.00%
  2. Glossodynia (a burning or painful sensation in the tongue): 34 people, 100.00%
  3. Nasopharyngitis (inflammation of the nasopharynx): 34 people, 100.00%
  4. Liver Injury: 34 people, 100.00%
  5. High Blood Pressure: 34 people, 100.00%
  6. Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 34 people, 100.00%
  7. Headache (pain in head): 34 people, 100.00%
  8. Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 34 people, 100.00%
  9. Rheumatic Fever (an inflammatory disease that occurs following a streptococcus pyogenes infection): 34 people, 100.00%
  10. Weakness: 34 people, 100.00%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 34 people, 100.00%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 34 people, 100.00%
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints): 26 people, 76.47%
  4. Psoriasis (immune-mediated disease that affects the skin): 18 people, 52.94%
  5. Stress And Anxiety: 17 people, 50.00%
  6. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 10 people, 29.41%
  7. Synovitis (inflammation of the synovial membrane): 7 people, 20.59%
  8. Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 7 people, 20.59%
  9. Drug Ineffective: 5 people, 14.71%
  10. Headache (pain in head): 5 people, 14.71%

* Approximation only. Some reports may have incomplete information.

Do you take Zyrtec and have Lupus vulgaris?

- Check whether Lupus vulgaris is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyrtec:

Lupus vulgaris treatments and more:

How severe was Lupus vulgaris and when was it recovered:

Expand to all the drugs that have ingredients of cetirizine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lupus vulgaris:

Browse all the conditions that are associated with Lupus vulgaris:


How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride (the active ingredients of Zyrtec) and Zyrtec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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