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Confusion and drugs of ingredients of bupropion hydrochloride (a real world drug study)


Summary:

Confusion is found among people who take drugs with ingredients of bupropion hydrochloride, especially for people who are female, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 179,375 people who have side effects when taking drugs with ingredients of bupropion hydrochloride from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Aplenzin, Bupropion hydrobromide, Bupropion hydrochloride, Forfivo xl, Wellbutrin, Wellbutrin sr, Wellbutrin xl, Zyban.

On Jan, 11, 2026

179,375 people reported to have side effects when taking drugs with ingredients of bupropion hydrochloride.
Among them, 1,259 people (0.7%) have Confusion

What is Confusion?

Confusion is found to be associated with 1,838 drugs and 2,815 conditions by eHealthMe. Check the latest studies of Confusion.

Number of reports submitted per year:

Could drugs with ingredients of bupropion hydrochloride cause Confusion?

Time on drugs with ingredients of bupropion hydrochloride when people have Confusion *:

  • < 1 month: 62.93 %
  • 1 - 6 months: 14.66 %
  • 6 - 12 months: 6.9 %
  • 1 - 2 years: 4.31 %
  • 2 - 5 years: 8.62 %
  • 5 - 10 years: 0.86 %
  • 10+ years: 1.72 %

Gender of people who have Confusion when taking drugs with ingredients of bupropion hydrochloride *:

  • female: 60.4 %
  • male: 39.6 %

Age of people who have Confusion when taking drugs with ingredients of bupropion hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 0.29 %
  • 10-19: 5.12 %
  • 20-29: 10.43 %
  • 30-39: 14.69 %
  • 40-49: 21.84 %
  • 50-59: 23.19 %
  • 60+: 24.44 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Pain: 64 people, 5.08%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 61 people, 4.85%
  3. Insomnia (sleeplessness): 53 people, 4.21%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 40 people, 3.18%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 32 people, 2.54%
  6. Bipolar Disorder (mood disorder): 26 people, 2.07%
  7. High Blood Cholesterol: 25 people, 1.99%
  8. High Blood Pressure: 25 people, 1.99%
  9. Sleep Disorder: 25 people, 1.99%
  10. Hepatitis C: 19 people, 1.51%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Xanax: 81 people, 6.43%
  2. Xyrem: 68 people, 5.40%
  3. Clonazepam: 59 people, 4.69%
  4. Seroquel: 57 people, 4.53%
  5. Neurontin: 56 people, 4.45%
  6. Prilosec: 54 people, 4.29%
  7. Synthroid: 54 people, 4.29%
  8. Lexapro: 52 people, 4.13%
  9. Cymbalta: 51 people, 4.05%
  10. Zoloft: 50 people, 3.97%

Other side effects people have besides Confusion *:

You may use this to check any potential undetected side effects.

  1. Confusional State: 223 people, 17.71%
  2. Nausea (feeling of having an urge to vomit): 215 people, 17.08%
  3. Agitation (state of anxiety or nervous excitement): 213 people, 16.92%
  4. Fatigue (feeling of tiredness): 208 people, 16.52%
  5. Weakness: 186 people, 14.77%
  6. Memory Loss: 183 people, 14.54%
  7. Dizziness: 181 people, 14.38%
  8. Fall: 147 people, 11.68%
  9. Tremor (trembling or shaking movements in one or more parts of your body): 138 people, 10.96%
  10. Feeling Abnormal: 125 people, 9.93%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of bupropion hydrochloride, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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