Personalized prediction for a 40 year old woman who takes Mefenamic Acid, Levothyroxine Thyroid, Tranexamic Acid, Methylphenidate Hydrochloride (an AI-powered real world drug study)
Summary:
This is a personalized prediction of potential side effects and undetected conditions for up to one year, if you would have adverse effects. The study is created by eHealthMe based on data from the FDA.
On Sep, 26, 2025, 8,046,621 related reports were analyzed:

What are the drugs?
- Mefenamic acid has active ingredients of mefenamic acid. It is often used in painful menstrual periods. eHealthMe is studying from 4,844 Mefenamic acid users. Check the latest studies of Mefenamic acid.
- Levothyroxine thyroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 4,032 Levothyroxine thyroid users. Check the latest studies of Levothyroxine thyroid.
- Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,686 Tranexamic acid users. Check the latest studies of Tranexamic acid.
- Methylphenidate hydrochloride has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 6,821 Methylphenidate hydrochloride users. Check the latest studies of Methylphenidate hydrochloride.
What are the conditions?
- Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease) is found to be associated with 1,030 drugs and 1,079 conditions by eHealthMe. Check the latest studies of Autoimmune thyroiditis.
- Adhd (adhd-mental disorders that develop in children) is found to be associated with 607 drugs and 1,367 conditions by eHealthMe. Check the latest studies of Adhd.
- Adenomyosis (presence of ectopic glandular tissue found in muscle) is found to be associated with 179 drugs and 246 conditions by eHealthMe. Check the latest studies of Adenomyosis.
What are the symtoms?
- Paleness (unusual lightness of skin colour) is found to be associated with 1,721 drugs and 2,103 conditions by eHealthMe. Check the latest studies of Paleness.
- Dizziness is found to be associated with 3,564 drugs and 5,667 conditions by eHealthMe. Check the latest studies of Dizziness.
- Fatigue aggravated (feeling of tiredness) is found to be associated with 2,596 drugs and 1,071 conditions by eHealthMe. Check the latest studies of Fatigue aggravated.
- Nausea (feeling of having an urge to vomit) is found to be associated with 3,794 drugs and 5,618 conditions by eHealthMe. Check the latest studies of Nausea.
Potential side effects:
- 5.59% for females aged 40 (±5) who have adenomyosis
- 5.05% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 6.29% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 6.65% for females aged 40 (±5) who have autoimmune thyroiditis and adhd
- 6.62% for females aged 40 (±5) who have adenomyosis and adhd
- 6.03% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 5.41% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 8.29% for females aged 40 (±5) who have adenomyosis and adhd
- 7.51% for females aged 40 (±5) who have autoimmune thyroiditis and adhd
- 6.85% for females aged 40 (±5) who have adenomyosis and adhd
- 6.0% for females aged 40 (±5) who have autoimmune thyroiditis and adhd
- 19.72% for females aged 40 (±5) who have adenomyosis and adhd
- 16.96% for females aged 40 (±5) who have autoimmune thyroiditis and adhd
- 6.1% for females aged 40 (±5) who take tranexamic acid
- 6.1% for females aged 40 (±5) who take methylphenidate hydrochloride
- 6.1% for females aged 40 (±5) who take mefenamic acid
- 6.1% for females aged 40 (±5) who take levothyroxine thyroid
- 5.14% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 5.59% for females aged 40 (±5) who have adenomyosis
- 20.57% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 15.52% for females aged 40 (±5) who have autoimmune thyroiditis and adhd
- 12.81% for females aged 40 (±5) who have adenomyosis and adhd
- 6.46% for females aged 40 (±5) who take mefenamic acid
- 6.46% for females aged 40 (±5) who take methylphenidate hydrochloride
- 6.46% for females aged 40 (±5) who take levothyroxine thyroid
- 6.46% for females aged 40 (±5) who take tranexamic acid
- 9.01% for females aged 40 (±5) who have adenomyosis and adhd
- 8.18% for females aged 40 (±5) who have autoimmune thyroiditis and adhd
- 8.42% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 13.5% for females aged 40 (±5) who have adenomyosis and adhd
- 13.5% for females aged 40 (±5) who have autoimmune thyroiditis and adhd
- 12.68% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 5.87% for females aged 40 (±5) who take tranexamic acid
- 5.87% for females aged 40 (±5) who take methylphenidate hydrochloride
- 5.87% for females aged 40 (±5) who take mefenamic acid
- 5.87% for females aged 40 (±5) who take levothyroxine thyroid
- 5.41% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 6.29% for females aged 40 (±5) who have adenomyosis
- 9.79% for females aged 40 (±5) who have adenomyosis
- 5.58% for females aged 40 (±5) who have autoimmune thyroiditis
- 7.45% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 6.74% for females aged 40 (±5) who have autoimmune thyroiditis and adhd
- 6.04% for females aged 40 (±5) who have adenomyosis and adhd
- 6.47% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 5.05% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 5.14% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 5.14% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 6.03% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 5.28% for females aged 40 (±5) who have autoimmune thyroiditis
- 5.59% for females aged 40 (±5) who have adenomyosis
- 5.05% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 6.58% for females aged 40 (±5) who have paleness and dizziness with adenomyosis and adhd
- 6.99% for females aged 40 (±5) who have adenomyosis
- 10.31% for females aged 40 (±5) who have adenomyosis and adhd
- 9.83% for females aged 40 (±5) who have autoimmune thyroiditis and adhd
- 7.36% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 5.59% for females aged 40 (±5) who have adenomyosis
- 8.69% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 12.59% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 5.14% for females aged 40 (±5) who have autoimmune thyroiditis and adhd
Potential co-existing conditions:
- 6.99% for females aged 40 (±5) who have adenomyosis
- 7.69% for females aged 40 (±5) who have adenomyosis
- 6.74% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 5.58% for females aged 40 (±5) who have autoimmune thyroiditis
- 5.5% for females aged 40 (±5) who have adenomyosis and autoimmune thyroiditis
- 12.59% for females aged 40 (±5) who have adenomyosis
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
How the study uses the data?
The study is based on gender, age, active ingredients of any drugs used, and more. Other drugs that have the same active ingredients (e.g. generic drugs) are considered.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
Related publications that referenced our studies
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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