Abilify and Amantadine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abilify (aripiprazole) and Amantadine hydrochloride (amantadine hydrochloride). Common drug interactions include acute coronary syndrome among females and neuroleptic malignant syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Abilify and Amantadine hydrochloride. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.

What is Amantadine hydrochloride?

Amantadine hydrochloride has active ingredients of amantadine hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 2,398 Amantadine hydrochloride users. Check the latest studies of Amantadine hydrochloride.

On Jul, 17, 2026

14 people who take Abilify and Amantadine hydrochloride together, and have interactions are studied.

Abilify and Amantadine hydrochloride drug interactions.

What are the common drug interactions of Abilify and Amantadine Hydrochloride, by gender? *:

female:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Arteriosclerosis (thickening and hardening of arteries)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Malaise (a feeling of general discomfort or uneasiness)
Pallor
Respiratory distress (difficulty in breathing)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Tooth disorder (tooth disease)

male:

Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Pneumonia
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Intestinal obstruction
Therapeutic response unexpected
Vomiting
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Renal impairment (severely reduced kidney function)
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the common drug interactions of Abilify and Amantadine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Respiratory distress (difficulty in breathing)

40-49:

Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Pneumonia
Ileus (a painful obstruction of the ileum or other part of the intestine)
Renal impairment (severely reduced kidney function)
Respiratory failure (inadequate gas exchange by the respiratory system)
Death

50-59:

Arteriosclerosis (thickening and hardening of arteries)
Colitis (inflammation of colon)
Intestinal obstruction
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)

60+:

Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Blood glucose decreased
Cerebral infarction (less blood supply to brain resulting tissue damage)
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Malaise (a feeling of general discomfort or uneasiness)
Pallor
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Tooth disorder (tooth disease)
Vomiting

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 21.43%
Bipolar Disorder (mood disorder): 3 people, 21.43%
Stress And Anxiety: 1 person, 7.14%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 7.14%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 7.14%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 7.14%
Hallucination, Auditory (perceiving sounds without auditory stimulus): 1 person, 7.14%
Gaze Palsy (disorders affecting the ability to move both eyes in the same direction): 1 person, 7.14%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 1 person, 7.14%
Delusion (a false belief or opinion): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Abilify and Amantadine hydrochloride?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously