Acetaminophen and Casodex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Acetaminophen (acetaminophen) and Casodex (bicalutamide). Common drug interactions include fatigue among females and osteonecrosis of jaw among males.
The phase IV clinical study analyzes what interactions people have when they take Acetaminophen and Casodex. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.
What is Acetaminophen?
Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.
What is Casodex?
Casodex has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 10,725 Casodex users. Check the latest studies of Casodex.
80 people who take Acetaminophen and Casodex together, and have interactions are studied.

What are the common drug interactions of Acetaminophen and Casodex, by gender? *:
female:
- Fatigue (feeling of tiredness)
- Metastases to bone (cancer spreads to bone)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Prostatic specific antigen increased
- Abasia (inability to walk)
- Actinic keratosis (skin disease due to sun exposure)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anxiety
- Aortic arteriosclerosis (hardening of the aortic arteries)
- Arachnoid cyst
male:
- Osteonecrosis of jaw (death of bone of jaw)
- Anxiety
- Metastases to bone (cancer spreads to bone)
- Neoplasm malignant (cancer tumour)
- Osteomyelitis (infection of bone)
- Spinal osteoarthritis (joint cartilage loss in spine)
- Weight decreased
- Back pain
- Dizziness
- Prostatic specific antigen increased
What are the common drug interactions of Acetaminophen and Casodex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bipolar disorder (mood disorder)
- Chest pain
- Chills (felling of cold)
- Constipation
- Dyspnoea (difficult or laboured respiration)
- Dysuria (painful or difficult urination)
- Fatigue (feeling of tiredness)
50-59:
- Arthralgia (joint pain)
- Asthenia (weakness)
- Back pain
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Haemorrhage (bleeding)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Dizziness
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Abasia (inability to walk)
- Actinic keratosis (skin disease due to sun exposure)
60+:
- Weight decreased
- Metastases to bone (cancer spreads to bone)
- Anaemia (lack of blood)
- Injury
- Joint swelling
- Asthenia (weakness)
- Constipation
- Dyspnoea (difficult or laboured respiration)
- Fall
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
What are the existing conditions these people have? *
- Prostate Cancer Metastatic: 15 people, 18.75%
- Constipation: 8 people, 10.00%
- High Blood Pressure: 7 people, 8.75%
- Neoplasm Malignant (cancer tumour): 6 people, 7.50%
- Metastases To Bone (cancer spreads to bone): 6 people, 7.50%
* Approximation only. Some reports may have incomplete information.
Do you take Acetaminophen and Casodex?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Acetaminophen (183,077 reports)
- Casodex (10,725 reports)
Browse all drug interactions of Acetaminophen and Casodex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Acetaminophen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Casodex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acetaminophen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Casodex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on acetaminophen and bicalutamide (the active ingredients of Acetaminophen and Casodex, respectively), and Acetaminophen and Casodex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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