Acetaminophen and Cytotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetaminophen (acetaminophen) and Cytotec (misoprostol). Common drug interactions include pneumonia aspiration among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Acetaminophen and Cytotec. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Cytotec?

Cytotec has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 5,812 Cytotec users. Check the latest studies of Cytotec.



On Jul, 10, 2026

75 people who take Acetaminophen and Cytotec together, and have interactions are studied.

Acetaminophen and Cytotec drug interactions.

What are the common drug interactions of Acetaminophen and Cytotec, by gender? *:

female:

  1. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  2. Pulmonary congestion (congestion in the lungs)
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Weight decreased
  5. White blood cell count decreased
  6. Abdominal pain upper
  7. Allergy
  8. Arthralgia (joint pain)
  9. Cardiac failure
  10. Colonic stenosis (abnormal narrowing of colon)

male:

  1. Back pain
  2. Constipation
  3. Oropharyngeal pain
  4. Productive cough
  5. Thrombotic cerebral infarction (death of cerebral tissue due to clot formation)
  6. Urinary tract infection
  7. Altered state of consciousness (altered state of mind)
  8. Aspartate aminotransferase increased
  9. Blood alkaline phosphatase increased
  10. C-reactive protein increased

What are the common drug interactions of Acetaminophen and Cytotec, by age (0-1 to 60+)? *:

0-1:

  1. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

2-9:

n/a

10-19:

n/a

20-29:

  1. General physical health deterioration (weak health status)
  2. Arthralgia (joint pain)
  3. Chills (felling of cold)
  4. Colonic stenosis (abnormal narrowing of colon)
  5. Depression
  6. Drug exposure during pregnancy
  7. Erythema (redness of the skin)
  8. Osteonecrosis (death of bone)
  9. Pyrexia (fever)
  10. Tremor (trembling or shaking movements in one or more parts of your body)

30-39:

  1. Blood pressure increased
  2. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  3. Glucose tolerance impaired in pregnancy (higher glucose level in pregnancy but not diabetes)
  4. Maternal exposure during pregnancy (use of substance during pregnancy)
  5. Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
  6. Premature labour
  7. Swelling
  8. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  9. Corneal disorder
  10. Corneal erosion (failure of the cornea's outermost layer of epithelial cells to attach to the underlying)

40-49:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Cellulitis (infection under the skin)
  3. Infusion site reaction
  4. Infusion site swelling
  5. Infusion site urticaria (rash of round, red welts on the skin at infusion site)
  6. Allergy
  7. Diarrhoea
  8. Discomfort
  9. Hepatitis acute
  10. Hypersensitivity

50-59:

  1. Disease progression
  2. Hypertension (high blood pressure)
  3. Keratitis interstitial (corneal scarring due to chronic inflammation)
  4. Lung adenocarcinoma stage iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver)
  5. Palpitations (feelings or sensations that your heart is pounding or racing)
  6. Pleurothotonus (neurological disorder which occurs due to prolonged exposure to antipsychotic drugs)
  7. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  8. Pyrexia (fever)
  9. Sinusitis (inflammation of sinus)
  10. Weight increased

60+:

  1. Back pain
  2. Constipation
  3. Dyslipidaemia (abnormal amount of lipids)
  4. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  5. Oropharyngeal pain
  6. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  7. Productive cough
  8. Thrombotic cerebral infarction (death of cerebral tissue due to clot formation)
  9. Urinary tract infection
  10. White blood cell count decreased

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 17.33%
  2. Constipation: 10 people, 13.33%
  3. Labor Induction: 8 people, 10.67%
  4. Iron Deficiency: 7 people, 9.33%
  5. Depression: 6 people, 8.00%
  6. Asthma: 6 people, 8.00%
  7. Renal Cell Carcinoma (a kidney cancer): 5 people, 6.67%
  8. Morning Sickness (sickness in morning during pregnancy): 5 people, 6.67%
  9. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 4 people, 5.33%
  10. High Blood Pressure: 4 people, 5.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acetaminophen and Cytotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cytotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acetaminophen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cytotec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen and misoprostol (the active ingredients of Acetaminophen and Cytotec, respectively), and Acetaminophen and Cytotec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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