Amoxicillin and Silybum drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxicillin (amoxicillin) and Silybum (milk thistle). Common drug interactions include pneumonia among females and metal poisoning among males.

The phase IV clinical study analyzes what interactions people have when they take Amoxicillin and Silybum. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Silybum?

Silybum has active ingredients of milk thistle. eHealthMe is studying from 779 Silybum users. Check the latest studies of Silybum.

On Jul, 12, 2026

51 people who take Amoxicillin and Silybum together, and have interactions are studied.

Amoxicillin and Silybum drug interactions.

What are the common drug interactions of Amoxicillin and Silybum, by gender? *:

female:

Pneumonia
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Infectious pleural effusion (infectious fluid in the lung)
Lower respiratory tract infection
Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
Pleural effusion (water on the lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal distension
Dental caries
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

male:

Metal poisoning
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Dysmorphism (difference of body structure that is suggestive of a congenital disorder)
Renal failure (kidney dysfunction)
Rib fracture
Abdominal infection
Bone loss
Haematemesis (vomiting of blood)
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)

What are the common drug interactions of Amoxicillin and Silybum, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthritis (form of joint disorder that involves inflammation of one or more joints)

40-49:

Abdominal distension
Euphoric mood (excessively happy but may become angry or irritable)
Fatigue (feeling of tiredness)
Therapeutic response decreased (less preventive response)
Tooth disorder (tooth disease)
Weight fluctuation
Abdominal pain upper
Decreased appetite
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)

50-59:

Pneumonia
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Atrophy (wasting away of a part of the body)
Chronic kidney disease
Dysmorphism (difference of body structure that is suggestive of a congenital disorder)
Emotional distress
Infectious pleural effusion (infectious fluid in the lung)
Lower respiratory tract infection

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Anaemia (lack of blood)
Chronic kidney disease
Hepatitis c
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)
Renal failure (kidney dysfunction)
Bone density decreased
Bone loss

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 23.53%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 19.61%
Hiv Infection: 6 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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