Arimidex and Methimazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arimidex (anastrozole) and Methimazole (methimazole). Common drug interactions include insomnia among females and adrenal insufficiency among males.

The phase IV clinical study analyzes what interactions people have when they take Arimidex and Methimazole. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Arimidex?

Arimidex has active ingredients of anastrozole. It is often used in breast cancer. eHealthMe is studying from 22,642 Arimidex users. Check the latest studies of Arimidex.

What is Methimazole?

Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 8,016 Methimazole users. Check the latest studies of Methimazole.



On Jul, 28, 2026

22 people who take Arimidex and Methimazole together, and have interactions are studied.

Arimidex and Methimazole drug interactions.

What are the common drug interactions of Arimidex and Methimazole, by gender? *:

female:

  1. Insomnia (sleeplessness)
  2. Abasia (inability to walk)
  3. Drug ineffective
  4. Dysstasia (difficulty in standing)
  5. Gait disturbance
  6. Myalgia (muscle pain)
  7. Adverse event
  8. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  9. Back pain
  10. Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)

male:

  1. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  2. Dehydration (dryness resulting from the removal of water)
  3. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  4. Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Upper respiratory tract infection
  7. Haematoma (collection of blood outside the blood vessels)
  8. Pancreatitis (inflammation of pancreas)
  9. Peritoneal haemorrhage (peritoneal bleeding)
  10. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)

What are the common drug interactions of Arimidex and Methimazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Hair colour changes
  3. Hair disorder
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Insomnia (sleeplessness)
  6. Joint swelling
  7. Pain in extremity
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  10. Dehydration (dryness resulting from the removal of water)

60+:

  1. Abasia (inability to walk)
  2. Dysstasia (difficulty in standing)
  3. Insomnia (sleeplessness)
  4. Low density lipoprotein increased (cholesterol increased in blood)
  5. Myalgia (muscle pain)
  6. Sleep disorder due to general medical condition, insomnia type (a conditions that prevent a person from getting restful sleep due to mental condition of not getting sleep)
  7. Activities of daily living impaired
  8. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  9. Anxiety
  10. Aortic valve incompetence

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 3 people, 13.64%
  2. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 13.64%
  3. Multiple Myeloma (cancer of the plasma cells): 2 people, 9.09%
  4. Gait Disturbance: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Arimidex and Methimazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Arimidex and Methimazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arimidex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Methimazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arimidex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methimazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on anastrozole and methimazole (the active ingredients of Arimidex and Methimazole, respectively), and Arimidex and Methimazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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