Arranon and Dexamethasone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Arranon (nelarabine) and Dexamethasone (dexamethasone). Common drug interactions include acidosis among females and blood creatine phosphokinase increased among males.
The phase IV clinical study analyzes what interactions people have when they take Arranon and Dexamethasone. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Arranon?
Arranon has active ingredients of nelarabine. eHealthMe is studying from 289 Arranon users. Check the latest studies of Arranon.
What is Dexamethasone?
Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.
14 people who take Arranon and Dexamethasone together, and have interactions are studied.

What are the common drug interactions of Arranon and Dexamethasone, by gender? *:
female:
- Acidosis (build-up of carbon dioxide in the blood)
- Hyperkalaemia (damage to or disease of the kidney)
- Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
- Hypotension (abnormally low blood pressure)
- Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat)
- Anaemia (lack of blood)
- Decreased appetite
- Diarrhoea
- Febrile neutropenia (fever with reduced white blood cells)
- Gastric mucosal lesion (lesion of stomach mucous membrane)
male:
- Blood creatine phosphokinase increased
- Hypoaesthesia (reduced sense of touch or sensation)
- Depressed level of consciousness
- Myalgia (muscle pain)
- Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Platelet count decreased
- Abnormal behaviour
- Abulia (lack of will or initiative)
- Confusional state
What are the common drug interactions of Arranon and Dexamethasone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Febrile neutropenia (fever with reduced white blood cells)
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Acidosis (build-up of carbon dioxide in the blood)
- Hyperkalaemia (damage to or disease of the kidney)
- Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
- Hypotension (abnormally low blood pressure)
- Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat)
- Anaemia (lack of blood)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Decreased appetite
20-29:
- Bone marrow tumour cell infiltration
- Thrombocytopenia (decrease of platelets in blood)
30-39:
n/a
40-49:
- Renal impairment (severely reduced kidney function)
50-59:
- Anaemia (lack of blood)
- Febrile neutropenia (fever with reduced white blood cells)
- Leukoencephalopathy (disease of the white matter in the brain)
- Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Platelet count decreased
- Abnormal behaviour
- Abulia (lack of will or initiative)
- Confusional state
- Disinhibition (loss of inhibition)
60+:
n/a
What are the existing conditions these people have? *
- Neoplasm Malignant (cancer tumour): 12 people, 85.71%
- T-Cell Type Acute Leukaemia (a form of cancer of the white blood cells): 6 people, 42.86%
- Precursor T-Lymphoblastic Lymphoma/leukaemia (precursor b-cell cancer): 4 people, 28.57%
- Pain In Extremity: 2 people, 14.29%
- Pain: 2 people, 14.29%
- Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 14.29%
- Fungal Infection: 2 people, 14.29%
- Febrile Neutropenia (fever with reduced white blood cells): 2 people, 14.29%
- Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 2 people, 14.29%
- White Blood Cell Count Decreased: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Arranon and Dexamethasone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Arranon (289 reports)
- Dexamethasone (161,927 reports)
Browse all drug interactions of Arranon and Dexamethasone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Arranon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dexamethasone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Arranon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dexamethasone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on nelarabine and dexamethasone (the active ingredients of Arranon and Dexamethasone, respectively), and Arranon and Dexamethasone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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