Benylin and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benylin (diphenhydramine hydrochloride) and Simvastatin (simvastatin). Common drug interactions include atrial fibrillation among females and hypoglycaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Benylin and Simvastatin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Benylin?

Benylin has active ingredients of diphenhydramine hydrochloride. It is often used in cough. eHealthMe is studying from 346 Benylin users. Check the latest studies of Benylin.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

On Jul, 27, 2026

13 people who take Benylin and Simvastatin together, and have interactions are studied.

Benylin and Simvastatin drug interactions.

What are the common drug interactions of Benylin and Simvastatin, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Drug ineffective
Gait disturbance
Hypotension (abnormally low blood pressure)
Insomnia (sleeplessness)
Suicidal ideation
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Therapeutic response unexpected
Infusion related reaction
Pneumonia

male:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Thrombocytopenia (decrease of platelets in blood)
Tremor (trembling or shaking movements in one or more parts of your body)
Abnormal loss of weight
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Bladder disorder
Blood creatinine increased
Blood pressure diastolic decreased

What are the common drug interactions of Benylin and Simvastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abnormal loss of weight
Bladder disorder
Blood urine present
Infusion related reaction
Pneumonia
Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Drug ineffective
Cardiac failure
Hypoglycaemia (deficiency of glucose in the bloodstream)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Thrombocytopenia (decrease of platelets in blood)
Gait disturbance
Hypotension (abnormally low blood pressure)
Insomnia (sleeplessness)

What are the existing conditions these people have? *

Pain: 6 people, 46.15%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 38.46%
Dry Eyes (lack of adequate tears): 5 people, 38.46%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 5 people, 38.46%
Hyperthyroidism (over activity of the thyroid gland): 5 people, 38.46%
Panic Disorder: 5 people, 38.46%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 5 people, 38.46%
Muscle Spasms (muscle contraction): 5 people, 38.46%
Nerve Compression: 5 people, 38.46%
Indigestion: 4 people, 30.77%

* Approximation only. Some reports may have incomplete information.

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