Casodex and Oxybutynin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Casodex (bicalutamide) and Oxybutynin (oxybutynin). Common drug interactions include asthenia among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Casodex and Oxybutynin. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Casodex?
Casodex has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 10,725 Casodex users. Check the latest studies of Casodex.
What is Oxybutynin?
Oxybutynin has active ingredients of oxybutynin. It is often used in urge incontinence. eHealthMe is studying from 23,143 Oxybutynin users. Check the latest studies of Oxybutynin.
21 people who take Casodex and Oxybutynin together, and have interactions are studied.

What are the common drug interactions of Casodex and Oxybutynin, by gender? *:
female:
- Asthenia (weakness)
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Bone disorder
- Cerebral atrophy (decrement in size of brain)
- Chest pain
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Constipation
- Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
- Fall
male:
- Fatigue (feeling of tiredness)
- Dizziness
- Dysphagia (a condition in which swallowing is difficult or painful)
- Hyperkalaemia (damage to or disease of the kidney)
- Hypertension (high blood pressure)
- Malignant neoplasm progression (cancer tumour came back)
- Neuropathy peripheral (surface nerve damage)
- Pain in extremity
- Urinary incontinence (inability to control the flow of urine and involuntary urination)
- Abdominal pain upper
What are the common drug interactions of Casodex and Oxybutynin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abdominal discomfort
- Abdominal pain upper
- Abscess (pus)
- Actinomycosis (infection that causes sores, or abscesses)
- Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Anaemia (lack of blood)
- Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Angiopathy (generic term for a disease of the blood vessels)
- Anisocytosis (patient's red blood cells are of unequal size)
40-49:
n/a
50-59:
- Gynaecomastia (enlargement of the gland tissue of the male breast)
- Haematocrit decreased
- Haemoglobin decreased
- Haemorrhage (bleeding)
- Head injury
- Headache (pain in head)
- Hearing impaired
- Herpes zoster
- Hypoaesthesia (reduced sense of touch or sensation)
- Infection
60+:
- Fatigue (feeling of tiredness)
- Hot flush (sudden feelings of heat)
- Dehydration (dryness resulting from the removal of water)
- Depressed mood
- Disease progression
- Dizziness
- Drug ineffective
- Dysgeusia (disorder of the sense of taste)
- Dysuria (painful or difficult urination)
- Eyelid ptosis (falling of the upper or lower eyelid)
What are the existing conditions these people have? *
- Prostate Cancer Metastatic: 2 people, 9.52%
- Metastases To Bone (cancer spreads to bone): 2 people, 9.52%
- High Blood Pressure: 2 people, 9.52%
* Approximation only. Some reports may have incomplete information.
Do you take Casodex and Oxybutynin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Casodex (10,725 reports)
- Oxybutynin (23,143 reports)
Browse all drug interactions of Casodex and Oxybutynin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Casodex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Oxybutynin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Casodex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Oxybutynin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on bicalutamide and oxybutynin (the active ingredients of Casodex and Oxybutynin, respectively), and Casodex and Oxybutynin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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