Celexa and Daytrana drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Celexa (citalopram hydrobromide) and Daytrana (methylphenidate). Common drug interactions include aneurysm ruptured among females and application site erythema among males.

The phase IV clinical study analyzes what interactions people have when they take Celexa and Daytrana. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Celexa?

Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,390 Celexa users. Check the latest studies of Celexa.

What is Daytrana?

Daytrana has active ingredients of methylphenidate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 16,561 Daytrana users. Check the latest studies of Daytrana.



On Jul, 14, 2026

52 people who take Celexa and Daytrana together, and have interactions are studied.

Celexa and Daytrana drug interactions.

What are the common drug interactions of Celexa and Daytrana, by gender? *:

female:

  1. Aneurysm ruptured (expansion of the aneurysm reaches a point where the wall becomes too thin, the aneurysm will rupture)
  2. Drug administration error
  3. Overdose
  4. Retinal aneurysm (an abnormal dilatation of an retinal artery)
  5. Anaemia (lack of blood)
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Abdominal discomfort
  8. Cerebral haemorrhage (bleeding within the brain)
  9. Decreased appetite
  10. Disturbance in social behaviour

male:

  1. Application site erythema (redness of the skin at application site)
  2. Application site rash
  3. Abnormal behaviour
  4. Accidental exposure
  5. Appendicitis (inflammation of the appendix)
  6. Application site dryness
  7. Application site irritation
  8. Application site pain
  9. Application site pruritus (application site severe itching of the skin)
  10. Application site swelling

What are the common drug interactions of Celexa and Daytrana, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Drug effect delayed
  2. Appendicitis (inflammation of the appendix)
  3. Application site swelling
  4. Drug administration error
  5. Drug ineffective
  6. Application site erythema (redness of the skin at application site)

10-19:

  1. Application site erythema (redness of the skin at application site)
  2. Drug ineffective
  3. Drug administration error
  4. Impulse-control disorder
  5. Overdose
  6. Psychomotor hyperactivity (feelings of extreme restlessness)
  7. Anaemia (lack of blood)
  8. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  9. Abdominal discomfort
  10. Abdominal pain upper

20-29:

  1. Disturbance in attention
  2. Irritability
  3. Drug administration error

30-39:

n/a

40-49:

  1. Aneurysm ruptured (expansion of the aneurysm reaches a point where the wall becomes too thin, the aneurysm will rupture)
  2. Retinal aneurysm (an abnormal dilatation of an retinal artery)
  3. Cerebral haemorrhage (bleeding within the brain)
  4. Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
  5. Medical device complication
  6. Post procedural complication

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Stress And Anxiety: 13 people, 25.00%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

Do you take Celexa and Daytrana?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Celexa and Daytrana:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Celexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Daytrana:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Celexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daytrana and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on citalopram hydrobromide and methylphenidate (the active ingredients of Celexa and Daytrana, respectively), and Celexa and Daytrana (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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