Clolar and Dexamethasone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clolar (clofarabine) and Dexamethasone (dexamethasone). Common drug interactions include acute lymphocytic leukaemia among females and thrombocytopenia among males.
The phase IV clinical study analyzes what interactions people have when they take Clolar and Dexamethasone. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.
What is Clolar?
Clolar has active ingredients of clofarabine. eHealthMe is studying from 1,093 Clolar users. Check the latest studies of Clolar.
What is Dexamethasone?
Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.
50 people who take Clolar and Dexamethasone together, and have interactions are studied.

What are the common drug interactions of Clolar and Dexamethasone, by gender? *:
female:
- Acute lymphocytic leukaemia (cancer of the white blood cells)
- Blood pressure increased
- Contusion (a type of hematoma of tissue in which capillaries)
- Device related infection
- Epistaxis (bleed from the nose)
- Gastrointestinal fungal infection
- Haematemesis (vomiting of blood)
- Nausea (feeling of having an urge to vomit)
- Neutropenia (an abnormally low number of neutrophils)
- Oral candidiasis (fungal infection of mouth)
male:
- Thrombocytopenia (decrease of platelets in blood)
- Febrile neutropenia (fever with reduced white blood cells)
- Pleural effusion (water on the lungs)
- Renal tubular necrosis (death of kidney tubules)
- Small intestinal obstruction (blockage in small intestine)
- Hypokalaemia (low potassium)
- Infection
- Staphylococcal bacteraemia (a bacterial infection of blood)
- Acute respiratory distress syndrome
- Capillary leak syndrome (capillary leaks plasma)
What are the common drug interactions of Clolar and Dexamethasone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Abdominal pain
- Anaemia (lack of blood)
- Blood pressure increased
- Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
- Cardiomegaly (increased size of heart than normal)
- Catheter site erosion
- Catheter site erythema (redness of skin at catheter site)
- Cellulitis (infection under the skin)
- Chest pain
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
10-19:
- Epistaxis (bleed from the nose)
- Febrile neutropenia (fever with reduced white blood cells)
- Haematemesis (vomiting of blood)
- Pain in extremity
- Vomiting
- Acute lymphocytic leukaemia (cancer of the white blood cells)
- Appendicitis (inflammation of the appendix)
- Blood pressure increased
- Contusion (a type of hematoma of tissue in which capillaries)
- Device related infection
20-29:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Sensory disturbance (sense disturbance)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Thrombocytopenia (decrease of platelets in blood)
- Febrile neutropenia (fever with reduced white blood cells)
- Dehydration (dryness resulting from the removal of water)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Abdominal pain
- Altered state of consciousness (altered state of mind)
- Appendicitis (inflammation of the appendix)
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Hypotension (abnormally low blood pressure)
- Aspartate aminotransferase increased
- Renal tubular necrosis (death of kidney tubules)
- Small intestinal obstruction (blockage in small intestine)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Cardiac arrest
- Coagulopathy (blood's ability to clot is impaired)
- Depressed level of consciousness
- Diastolic dysfunction
- Drug toxicity
What are the existing conditions these people have? *
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 17 people, 34.00%
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 15 people, 30.00%
- Acute Leukaemia (blood cancer): 5 people, 10.00%
- Haematological Malignancy (cancer that affect blood, bone marrow, and lymph nodes): 4 people, 8.00%
- Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 6.00%
- Herpes Zoster: 3 people, 6.00%
- Blood Fibrinogen Decreased: 3 people, 6.00%
* Approximation only. Some reports may have incomplete information.
Do you take Clolar and Dexamethasone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clolar (1,093 reports)
- Dexamethasone (161,927 reports)
Browse all drug interactions of Clolar and Dexamethasone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clolar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dexamethasone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clolar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dexamethasone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on clofarabine and dexamethasone (the active ingredients of Clolar and Dexamethasone, respectively), and Clolar and Dexamethasone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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