Creon and Estradiol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Creon (pancrelipase (amylase;lipase;protease)) and Estradiol (estradiol). Common drug interactions include diarrhoea among females.
The phase IV clinical study analyzes what interactions people have when they take Creon and Estradiol. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.
What is Creon?
Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.
What is Estradiol?
Estradiol has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 18,986 Estradiol users. Check the latest studies of Estradiol.
72 people who take Creon and Estradiol together, and have interactions are studied.

What are the common drug interactions of Creon and Estradiol, by gender? *:
female:
- Diarrhoea
- Fatigue (feeling of tiredness)
- Abdominal pain upper
- Cough
- Pyrexia (fever)
- Colitis (inflammation of colon)
- Fall
- Hypotension (abnormally low blood pressure)
- Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
- Pain in extremity
male:
n/a
What are the common drug interactions of Creon and Estradiol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal discomfort
- Abnormal behaviour
- Application site burn
- Application site irritation
- Application site pruritus (application site severe itching of the skin)
- Back pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Constipation
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Cough
50-59:
- Injection site rash
- Osteonecrosis (death of bone)
- Pelvic fracture
- Abdominal pain upper
- Agitation (state of anxiety or nervous excitement)
- Anxiety
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
- Campylobacter gastroenteritis (infection of gastrointestinal system)
- Campylobacter infection (infection by the campylobacter bacterium)
60+:
- Abdominal pain
- Fatigue (feeling of tiredness)
- Anaemia (lack of blood)
- Arrhythmia (irregular heartbeat)
- Arthropathy
- Cataract (clouding of the lens inside the eye)
- Eating disorder
- Fall
- Feeling cold
- Fistula (an abnormal connection or passageway between two)
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 14 people, 19.44%
- Cystic Fibrosis (disease of the secretary glands): 13 people, 18.06%
- Pancreatic Carcinoma (pancreatic cancer): 7 people, 9.72%
- Asthma: 6 people, 8.33%
- Pulmonary Embolism (blockage of the main artery of the lung): 5 people, 6.94%
- Insomnia (sleeplessness): 5 people, 6.94%
- Aplasia Pure Red Cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells): 5 people, 6.94%
- Urinary Tract Infection: 4 people, 5.56%
- Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 4 people, 5.56%
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 4 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Creon and Estradiol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Creon and Estradiol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Creon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Estradiol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Creon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Estradiol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) and estradiol (the active ingredients of Creon and Estradiol, respectively), and Creon and Estradiol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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