Depakote er and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Depakote er (divalproex sodium) and Acyclovir (acyclovir). Common drug interactions include culture wound positive among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Depakote er and Acyclovir. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Depakote er?

Depakote er has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 6,042 Depakote er users. Check the latest studies of Depakote er.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

On Jul, 14, 2026

33 people who take Depakote er and Acyclovir together, and have interactions are studied.

Depakote er and Acyclovir drug interactions.

What are the common drug interactions of Depakote Er and Acyclovir, by gender? *:

female:

Culture wound positive
Cystitis interstitial (unknown cause characterized by bladder pain)
Depression
Device occlusion
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Fall

male:

Fall
Abdominal distension
Diarrhoea
Dizziness
Drug ineffective
Dysuria (painful or difficult urination)
Erythema (redness of the skin)
Feeding disorder (when children refuse to eat certain food groups)
Gynaecomastia (enlargement of the gland tissue of the male breast)
Haemorrhage (bleeding)

What are the common drug interactions of Depakote Er and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Synovial cyst (cyst of joint filled with synovial fluid)
Varicose vein (veins that have become enlarged and tortuous)
Vitamin d deficiency
Influenza
Kidney infection
Sinus headache (headache caused by sinus infections)
Stress

40-49:

Accident
Back pain
Blood cholesterol increased
Blood triglycerides increased
Chest pain
Constipation
Cough
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dysuria (painful or difficult urination)
Headache (pain in head)

50-59:

Cellulitis (infection under the skin)
Urinary tract infection
Abdominal distension
Abdominal pain
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Back pain
Bladder disorder
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

Pneumonia
Confusional state
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug intolerance (drug sensitivity)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Tremor (trembling or shaking movements in one or more parts of your body)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dysarthria (speech disorder)
Fall
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 13 people, 39.39%
Pain: 11 people, 33.33%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 7 people, 21.21%
Oral Infection: 7 people, 21.21%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 21.21%
Migraine (headache): 7 people, 21.21%
Memory Loss: 7 people, 21.21%
Dizziness: 7 people, 21.21%
Pneumonia: 4 people, 12.12%
Herpes Zoster: 4 people, 12.12%

* Approximation only. Some reports may have incomplete information.

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