Dexamethasone and Tygacil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexamethasone (dexamethasone) and Tygacil (tigecycline). Common drug interactions include leukopenia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Dexamethasone and Tygacil. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.

What is Tygacil?

Tygacil has active ingredients of tigecycline. eHealthMe is studying from 2,129 Tygacil users. Check the latest studies of Tygacil.

On Jul, 11, 2026

12 people who take Dexamethasone and Tygacil together, and have interactions are studied.

Dexamethasone and Tygacil drug interactions.

What are the common drug interactions of Dexamethasone and Tygacil, by gender? *:

female:

Leukopenia (less number of white blood cells in blood)
Intestinal perforation (complete penetration of the wall of the intestine)
Thrombocytopenia (decrease of platelets in blood)
Diarrhoea
Haematoma (collection of blood outside the blood vessels)
Haemorrhagic diathesis (bleeding tendency)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Infection
Lung disorder (lung disease)
Nausea (feeling of having an urge to vomit)

male:

Pneumonia
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Vertigo
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone marrow failure
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)
Renal failure acute (rapid kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Dexamethasone and Tygacil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Intestinal perforation (complete penetration of the wall of the intestine)
Sepsis (a severe blood infection that can lead to organ failure and death)

10-19:

n/a

20-29:

Alanine aminotransferase increased
Ascites (accumulation of fluid in the abdominal cavity)
Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Erythema (redness of the skin)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hypotension (abnormally low blood pressure)
Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)
Skin nodule (slightly elevated lesions on or in the skin)
Vaginal cellulitis (vaginal spreading skin infection)

30-39:

n/a

40-49:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Gastrointestinal stoma complication (complication of an opening surgically made in digestive tract)
Hypotension (abnormally low blood pressure)
Multi-organ failure (multisystem organ failure)
Peritoneal disorder
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

n/a

60+:

Intestinal perforation (complete penetration of the wall of the intestine)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Vertigo
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone marrow failure
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 33.33%
Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins): 4 people, 33.33%
Stomatitis (inflammation of mucous membrane of mouth): 2 people, 16.67%
Respiratory Tract Infection: 2 people, 16.67%
Lymphohistiocytosis (an aggressive, life-threatening syndrome of excessive immune activation): 2 people, 16.67%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 16.67%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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