Dilacor xr and Lexapro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Dilacor xr (diltiazem hydrochloride) and Lexapro (escitalopram oxalate). Common drug interactions include irritable bowel syndrome among females and influenza among males.
The phase IV clinical study analyzes what interactions people have when they take Dilacor xr and Lexapro. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Dilacor xr?
Dilacor xr has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 870 Dilacor xr users. Check the latest studies of Dilacor xr.
What is Lexapro?
Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.
12 people who take Dilacor xr and Lexapro together, and have interactions are studied.

What are the common drug interactions of Dilacor Xr and Lexapro, by gender? *:
female:
- Irritable bowel syndrome
- Sinusitis (inflammation of sinus)
- Skin ulcer
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Pain in extremity
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Gastric ulcer (stomach ulcer)
- Gout (uric acid crystals building up in the body)
- Hypotension (abnormally low blood pressure)
male:
- Influenza
- Blood glucose increased
- Nausea (feeling of having an urge to vomit)
- Rectal haemorrhage (bleeding from anus)
- Vomiting
- Weight decreased
- White blood cell count decreased
What are the common drug interactions of Dilacor Xr and Lexapro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Chest pain
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Dyspnoea (difficult or laboured respiration)
- Gastric ulcer (stomach ulcer)
- Gout (uric acid crystals building up in the body)
- Hypotension (abnormally low blood pressure)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Irritable bowel syndrome
- Migraine (headache)
- Mitral valve prolapse (heart's mitral valve doesn't work well)
40-49:
- Bradycardia (abnormally slow heart action)
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Irritable bowel syndrome
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Pain in extremity
- Abdominal pain upper
- Activities of daily living impaired
- Agitation (state of anxiety or nervous excitement)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
50-59:
- Bone marrow disorder
- Fatigue (feeling of tiredness)
- Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
- Thrombosis (formation of a blood clot inside a blood vessel)
60+:
- Influenza
- Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
- Weight decreased
- White blood cell count decreased
- Arthralgia (joint pain)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood glucose increased
- Nausea (feeling of having an urge to vomit)
- Post procedural pulmonary embolism
- Postoperative ileus
What are the existing conditions these people have? *
- Migraine (headache): 4 people, 33.33%
- Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 25.00%
- Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 16.67%
- Pain: 2 people, 16.67%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 16.67%
- Type 2 Diabetes: 1 person, 8.33%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 8.33%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 8.33%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
- Diabetes: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Dilacor xr and Lexapro?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Dilacor xr (870 reports)
- Lexapro (91,464 reports)
Browse all drug interactions of Dilacor xr and Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dilacor xr:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dilacor xr and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lexapro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on diltiazem hydrochloride and escitalopram oxalate (the active ingredients of Dilacor xr and Lexapro, respectively), and Dilacor xr and Lexapro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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