Flonase and Apriso drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flonase (fluticasone propionate) and Apriso (mesalamine). Common drug interactions include cerebrovascular accident among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Flonase and Apriso. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

What is Apriso?

Apriso has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 3,439 Apriso users. Check the latest studies of Apriso.

On Jul, 07, 2026

47 people who take Flonase and Apriso together, and have interactions are studied.

What are the common drug interactions of Flonase and Apriso, by gender? *:

female:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chills (felling of cold)
Cough
Discomfort
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Drug effect decreased
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Ear infection

male:

Diarrhoea
Pyrexia (fever)
Post procedural infection
Arthralgia (joint pain)
Breast pain
Breast swelling
Cardiac failure congestive
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Eosinophil count increased
Flushing (the warm, red condition of human skin)

What are the common drug interactions of Flonase and Apriso, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Speech disorder developmental

10-19:

Drug effect decreased
Injection site erythema (redness at injection site)
Injection site pain

20-29:

n/a

30-39:

Arthralgia (joint pain)
Dehydration (dryness resulting from the removal of water)
Flushing (the warm, red condition of human skin)
Frequent bowel movements
Injection site haemorrhage (bleeding from injection site)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)

40-49:

Dyspepsia (indigestion)
Erythema (redness of the skin)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Peripheral swelling
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Arthralgia (joint pain)
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Flatulence (flatus expelled through the anus)
Haemorrhage (bleeding)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic fibrosis (scarring process that represents the liver's response to injury)
Injection site haemorrhage (bleeding from injection site)
Injection site pruritus (severe itching at injection site)
Pleural effusion (water on the lungs)

60+:

Insomnia (sleeplessness)
Anxiety
Cataract (clouding of the lens inside the eye)
Drug ineffective
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Glycosylated haemoglobin increased
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Mobility decreased (ability to move is reduced)
Muscle tightness

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 14 people, 29.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 27.66%
High Blood Pressure: 12 people, 25.53%
Pain: 9 people, 19.15%
Hypersensitivity: 7 people, 14.89%
Immunodeficiency Common Variable: 7 people, 14.89%
Depression: 6 people, 12.77%
High Blood Cholesterol: 6 people, 12.77%
Asthma: 5 people, 10.64%
Nausea (feeling of having an urge to vomit): 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

Do you take Flonase and Apriso?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously