Geodon and Fosamax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Geodon (ziprasidone hydrochloride) and Fosamax (alendronate sodium). Common drug interactions include tenderness among females and activities of daily living impaired among males.

The phase IV clinical study analyzes what interactions people have when they take Geodon and Fosamax. It is created by eHealthMe based on reports of 92 people who take the same drugs from the FDA, and is updated regularly.

What is Geodon?

Geodon has active ingredients of ziprasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 19,505 Geodon users. Check the latest studies of Geodon.

What is Fosamax?

Fosamax has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 105,452 Fosamax users. Check the latest studies of Fosamax.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

92 people who take Geodon and Fosamax together, and have interactions are studied.

What are the common drug interactions of Geodon and Fosamax, by gender? *:

female:

Tenderness (pain or discomfort when an affected area is touched)
Visual impairment
Wheezing (a high-pitched whistling sound made while you breath)
Dyspnoea (difficult or laboured respiration)
Oral pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Rash
Anaphylactic reaction (serious allergic reaction)
Drug intolerance (drug sensitivity)
Wound

male:

Activities of daily living impaired
Anaemia postoperative
Fracture nonunion (permanent failure of healing following a broken bone)
Gait disturbance
Groin pain
Hypoaesthesia (reduced sense of touch or sensation)
Impaired healing
Joint range of motion decreased (disease of joint movement)
Limb asymmetry (consistent task discrepancy between the two lower limbs)
Muscular weakness (muscle weakness)

What are the common drug interactions of Geodon and Fosamax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Activities of daily living impaired
Anaemia postoperative
Arthralgia (joint pain)
Bone pain
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Comminuted fracture (bone has broken into several pieces)
Fall
Femur fracture
Fracture delayed union (delayed cure of broken bone)
Fracture displacement

40-49:

Arthralgia (joint pain)
Anxiety
Biliary dilatation
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Faeces discoloured
Hyperglycaemia (high blood sugar)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Splenomegaly (enlargement of spleen)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

50-59:

Abdominal discomfort
Anaemia (lack of blood)
Anxiety
Arachnoid cyst
Arrhythmia (irregular heartbeat)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthrodesis
Arthropathy
Atrophy (wasting away of a part of the body)
Blood glucose increased

60+:

Abdominal pain
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Hypoaesthesia (reduced sense of touch or sensation)
Myalgia (muscle pain)
Rhinorrhoea (watery mucus discharge from the nose)
Dyspnoea (difficult or laboured respiration)
Appetite disorder (abnormal eating habits)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Back pain
Constipation

What are the existing conditions these people have? *

Dizziness: 37 people, 40.22%
High Blood Pressure: 13 people, 14.13%
Pain: 12 people, 13.04%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 10.87%
Depression: 9 people, 9.78%
Stress And Anxiety: 7 people, 7.61%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 6.52%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 6.52%
Sleep Disorder: 5 people, 5.43%

* Approximation only. Some reports may have incomplete information.

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