Ibuprofen and Velphoro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ibuprofen (ibuprofen) and Velphoro (sucroferric oxyhydroxide). Common drug interactions include chronic kidney disease among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Ibuprofen and Velphoro. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Velphoro?

Velphoro has active ingredients of sucroferric oxyhydroxide. eHealthMe is studying from 2,749 Velphoro users. Check the latest studies of Velphoro.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

14 people who take Ibuprofen and Velphoro together, and have interactions are studied.

Ibuprofen and Velphoro drug interactions.

What are the common drug interactions of Ibuprofen and Velphoro, by gender? *:

female:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Renal injury (kidney injury)
  5. Completed suicide (act of taking one's own life)
  6. Dysuria (painful or difficult urination)
  7. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  8. Overdose
  9. Renal hypertension (high blood pressure caused by the kidneys hormonal response)
  10. Urinary tract infection

male:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Renal injury (kidney injury)
  4. Secondary hyperthyroidism
  5. Dyspnoea (difficult or laboured respiration)
  6. Mobility decreased (ability to move is reduced)
  7. Post-traumatic stress disorder
  8. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  9. Renal impairment (severely reduced kidney function)
  10. Nephrogenic anaemia (anaemia due to kidney disease)

What are the common drug interactions of Ibuprofen and Velphoro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Renal injury (kidney injury)
  5. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  6. Renal hypertension (high blood pressure caused by the kidneys hormonal response)

40-49:

n/a

50-59:

  1. Emotional distress
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Decreased activity
  6. Fatigue (feeling of tiredness)
  7. Quality of life decreased
  8. Renal injury (kidney injury)
  9. Secondary hyperthyroidism
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Completed suicide (act of taking one's own life)
  5. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  6. Overdose
  7. Renal injury (kidney injury)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 64.29%
  2. High Blood Pressure: 8 people, 57.14%
  3. Fluid Retention (an abnormal accumulation of fluid in the blood): 7 people, 50.00%
  4. High Blood Cholesterol: 6 people, 42.86%
  5. Asthma: 4 people, 28.57%
  6. Bacterial Infection: 4 people, 28.57%
  7. Inflammation: 4 people, 28.57%
  8. Stress And Anxiety: 4 people, 28.57%
  9. Infection: 3 people, 21.43%
  10. Indigestion: 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ibuprofen and Velphoro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Velphoro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ibuprofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Velphoro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and sucroferric oxyhydroxide (the active ingredients of Ibuprofen and Velphoro, respectively), and Ibuprofen and Velphoro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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