Ispaghula and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ispaghula (blond psyllium) and Acetaminophen (acetaminophen). Common drug interactions include maternal exposure before pregnancy among females and sedation among males.

The phase IV clinical study analyzes what interactions people have when they take Ispaghula and Acetaminophen. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Ispaghula?

Ispaghula has active ingredients of blond psyllium. eHealthMe is studying from 737 Ispaghula users. Check the latest studies of Ispaghula.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Jul, 19, 2026

70 people who take Ispaghula and Acetaminophen together, and have interactions are studied.

Ispaghula and Acetaminophen drug interactions.

What are the common drug interactions of Ispaghula and Acetaminophen, by gender? *:

female:

Maternal exposure before pregnancy (use of substance before pregnancy)
Oedema peripheral (superficial swelling)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Renal pain (kidney pain)
Staphylococcal skin infection (skin infection by an infection with staphylococcus bacteria)
Tendon rupture (tear of tendon)
Toxic skin eruption (skin breakdown due to toxic substance)
Vomiting
Constipation
Balance disorder

male:

Sedation
Pyrexia (fever)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Myalgia (muscle pain)
Oedema peripheral (superficial swelling)
Rash erythematous (redness of the skin)
Renal failure (kidney dysfunction)
Peripheral swelling
Hypoproteinaemia (too little prolactin circulating in the blood)
Leukocytosis (increased white blood cells)

What are the common drug interactions of Ispaghula and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Choluria (presence of bile in urine)
Diarrhoea
Hepatic failure (liver failure)
Hepatomegaly (abnormal enlargement of the liver)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Myalgia (muscle pain)

40-49:

Dyspepsia (indigestion)
Fear of eating
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypertension (high blood pressure)
Pyrexia (fever)
Rectal haemorrhage (bleeding from anus)
Weight increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Dehydration (dryness resulting from the removal of water)

50-59:

Blood osmolarity decreased
Burning sensation
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

60+:

Sedation
Fall
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Bladder disorder
Dementia (madness)
Dyspnoea (difficult or laboured respiration)
Restlessness (not able to rest)
Drug abuse
Overdose
Bradycardia (abnormally slow heart action)

What are the existing conditions these people have? *

Bladder Disorder: 22 people, 31.43%
Urinary Tract Infection: 21 people, 30.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 21 people, 30.00%
Gastric Ulcer (stomach ulcer): 19 people, 27.14%
Chest Pain: 19 people, 27.14%
Constipation: 19 people, 27.14%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 19 people, 27.14%
Dementia (madness): 19 people, 27.14%
Fibromyalgia (a long-term condition which causes pain all over the body): 19 people, 27.14%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 19 people, 27.14%

* Approximation only. Some reports may have incomplete information.

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