Lamictal and Arimidex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamictal (lamotrigine) and Arimidex (anastrozole). Common drug interactions include osteomyelitis among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Lamictal and Arimidex. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.

What is Lamictal?

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,626 Lamictal users. Check the latest studies of Lamictal.

What is Arimidex?

Arimidex has active ingredients of anastrozole. It is often used in breast cancer. eHealthMe is studying from 22,642 Arimidex users. Check the latest studies of Arimidex.



On Jul, 13, 2026

96 people who take Lamictal and Arimidex together, and have interactions are studied.

Lamictal and Arimidex drug interactions.

What are the common drug interactions of Lamictal and Arimidex, by gender? *:

female:

  1. Osteomyelitis (infection of bone)
  2. Anxiety
  3. Decreased interest
  4. General physical health deterioration (weak health status)
  5. Hypertension (high blood pressure)
  6. Spinal osteoarthritis (joint cartilage loss in spine)
  7. Fall
  8. Bone disorder
  9. Constipation
  10. Metastases to spine (cancer spreads to spine)

male:

  1. Confusional state
  2. Anxiety
  3. Petit mal epilepsy (absence seizure)
  4. Dehydration (dryness resulting from the removal of water)
  5. Hypoaldosteronism (decreased levels of the hormone aldosterone)
  6. Renal failure (kidney dysfunction)
  7. Pain
  8. Essential hypertension (primary hypertension)
  9. Somnambulism (sleep walking)
  10. Headache (pain in head)

What are the common drug interactions of Lamictal and Arimidex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abscess jaw (tooth abscess or root abscess)
  2. Anxiety
  3. Arthralgia (joint pain)
  4. Arthropathy
  5. Asthenia (weakness)
  6. Ataxia (loss of full control of bodily movements)
  7. Back pain
  8. Balance disorder
  9. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  10. Bladder outlet obstruction (urological condition where the urine flow from the urinary bladder through the urethra is impeded)

20-29:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

30-39:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Anxiety
  4. Appendicitis (inflammation of the appendix)
  5. Arthropathy
  6. Asthma
  7. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  8. Bone pain
  9. Breast cancer recurrent
  10. Confusional state

40-49:

  1. Anxiety
  2. Aspartate aminotransferase increased
  3. Confusional state
  4. Disturbance in attention
  5. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  6. Hyperhidrosis (abnormally increased sweating)
  7. Hypermetabolism (abnormal increase in the body's basal metabolic rate)
  8. Night sweats (sweating in night)
  9. Petit mal epilepsy (absence seizure)
  10. Blood pressure increased

50-59:

  1. Constipation
  2. Dysphonia (speech disorder attributable to a disorder of phonation)
  3. Hot flush (sudden feelings of heat)
  4. Suicidal behaviour
  5. Adverse event
  6. Accident
  7. Anger
  8. Anxiety
  9. Asthenia (weakness)
  10. Back pain

60+:

  1. Foot fracture
  2. Bone disorder
  3. Back pain
  4. Blindness unilateral
  5. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  6. Candidiasis (candidiasis or thrush is a fungal infection)
  7. Cardiomegaly (increased size of heart than normal)
  8. Cellulitis (infection under the skin)
  9. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  10. Chromatopsia (visual defect in which colourless objects appear to be tinged with colour)

What are the existing conditions these people have? *

  1. Pain: 13 people, 13.54%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 13.54%
  3. Metastases To Bone (cancer spreads to bone): 12 people, 12.50%
  4. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 11 people, 11.46%
  5. Depression: 8 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Lamictal and Arimidex?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lamictal and Arimidex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamictal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Arimidex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lamictal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arimidex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine and anastrozole (the active ingredients of Lamictal and Arimidex, respectively), and Lamictal and Arimidex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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