Lamictal and Vancomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamictal (lamotrigine) and Vancomycin (vancomycin). Common drug interactions include sepsis among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Lamictal and Vancomycin. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Lamictal?

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,626 Lamictal users. Check the latest studies of Lamictal.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

On Jul, 18, 2026

41 people who take Lamictal and Vancomycin together, and have interactions are studied.

Lamictal and Vancomycin drug interactions.

What are the common drug interactions of Lamictal and Vancomycin, by gender? *:

female:

Sepsis (a severe blood infection that can lead to organ failure and death)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Renal failure (kidney dysfunction)
Blood bilirubin increased
Cerebellar infarction (impaired blood circulation to cerebellum)
Chronic kidney disease
Electrocardiogram qt prolonged
Febrile neutropenia (fever with reduced white blood cells)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

male:

Pneumonia
Catheter site infection (infection at the site of insertion)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Chemical burns of eye
Chronic kidney disease
Eye infection staphylococcal (staph eye infection are styes, large blisters in or around the eye, pain, swelling, and redness)
Eye injury
Eye irritation
Febrile neutropenia (fever with reduced white blood cells)
Hypoxia (low oxygen in tissues)

What are the common drug interactions of Lamictal and Vancomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cell death
Gamma-glutamyltransferase increased
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Toxic skin eruption (skin breakdown due to toxic substance)

30-39:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Anxiety
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Fibromyalgia (a long-term condition which causes pain all over the body)
Mania (a state of abnormally elevated or irritable mood)
Neuropathy peripheral (surface nerve damage)
Renal failure (kidney dysfunction)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)

40-49:

Catheter site infection (infection at the site of insertion)
Catheter site pain
Device dislocation
Hyperpyrexia (extremely high fever)
Pain in extremity
Pneumonia
Pyelonephritis (inflammation of kidney caused by bacteria)
Skin injury
Staphylococcal infection (an infection with staphylococcus bacteria)
Dermatitis allergic (inflammation of the skin due allergic reaction)

50-59:

Blood bilirubin increased
Cerebellar infarction (impaired blood circulation to cerebellum)
Electrocardiogram qt prolonged
Febrile neutropenia (fever with reduced white blood cells)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased
Rash
Chronic kidney disease
Renal failure (kidney dysfunction)
Drug eruption (adverse drug reaction of the skin)

60+:

Fall
Localised infection (infection at the single location)
Sepsis (a severe blood infection that can lead to organ failure and death)
Transfusion reaction (a serious problem that occurs after a patient receives a transfusion of blood)
Neck injury
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Arthralgia (joint pain)
Infusion site infection
Febrile neutropenia (fever with reduced white blood cells)
Hypoxia (low oxygen in tissues)

What are the existing conditions these people have? *

Pain: 18 people, 43.90%
High Blood Pressure: 15 people, 36.59%
Nausea (feeling of having an urge to vomit): 14 people, 34.15%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 14 people, 34.15%
Constipation: 12 people, 29.27%
Infection: 12 people, 29.27%
Liver Disorder (liver diseases): 12 people, 29.27%
Nasopharyngitis (inflammation of the nasopharynx): 12 people, 29.27%
Vitamin B1 Deficiency: 11 people, 26.83%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 11 people, 26.83%

* Approximation only. Some reports may have incomplete information.

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