Mitomycin and Ibuprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mitomycin (mitomycin) and Ibuprofen (ibuprofen). Common drug interactions include anal cancer among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Mitomycin and Ibuprofen. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Mitomycin?

Mitomycin has active ingredients of mitomycin. eHealthMe is studying from 4,195 Mitomycin users. Check the latest studies of Mitomycin.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

14 people who take Mitomycin and Ibuprofen together, and have interactions are studied.

Mitomycin and Ibuprofen drug interactions.

What are the common drug interactions of Mitomycin and Ibuprofen, by gender? *:

female:

  1. Anal cancer
  2. Fatigue (feeling of tiredness)
  3. Frequent bowel movements
  4. Hospitalisation
  5. Night sweats (sweating in night)
  6. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  7. Skin irritation
  8. Abdominal pain
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Anxiety

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  3. Chest pain
  4. Cough
  5. Disease progression
  6. Fatigue (feeling of tiredness)
  7. Gastroduodenal haemorrhage (bleeding from stomach or duodenum ulcer)
  8. Inappropriate antidiuretic hormone secretion
  9. Iron deficiency anaemia
  10. Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)

What are the common drug interactions of Mitomycin and Ibuprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Device dislocation
  5. Emotional distress
  6. Gastrointestinal injury (injury to gastrointestinal tract)
  7. General physical health deterioration (weak health status)
  8. Infection
  9. Injury
  10. Uterine perforation (accidental puncture of the uterus)

40-49:

  1. Fatigue (feeling of tiredness)
  2. Anal cancer
  3. Frequent bowel movements
  4. Hospitalisation
  5. Night sweats (sweating in night)
  6. Skin irritation
  7. Anorectal disorder
  8. Antidiuretic hormone abnormality
  9. Cauda equina syndrome (affecting the bundle of nerve roots)
  10. Chest pain

50-59:

  1. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  2. Inappropriate antidiuretic hormone secretion

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Hypotension (abnormally low blood pressure)
  3. Rash
  4. Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
  5. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  6. Urticaria (rash of round, red welts on the skin that itch intensely)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
  9. Oxygen saturation decreased
  10. Pyrexia (fever)

What are the existing conditions these people have? *

  1. Anal Cancer: 2 people, 14.29%
  2. Bronchial Carcinoma (lung cancer): 2 people, 14.29%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 14.29%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 14.29%
  5. Urination - Excessive Volume: 1 person, 7.14%
  6. Enlarged Prostate: 1 person, 7.14%
  7. Back Pain: 1 person, 7.14%
  8. Bladder Cancer: 1 person, 7.14%
  9. Dizziness: 1 person, 7.14%
  10. Dry Eyes (lack of adequate tears): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Mitomycin and Ibuprofen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mitomycin and Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mitomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mitomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ibuprofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mitomycin and ibuprofen (the active ingredients of Mitomycin and Ibuprofen, respectively), and Mitomycin and Ibuprofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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