Naproxen and Hyrimoz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Hyrimoz (adalimumab-adaz). Common drug interactions include hypokalaemia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Hyrimoz. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Hyrimoz?

Hyrimoz has active ingredients of adalimumab-adaz. eHealthMe is studying from 4,635 Hyrimoz users. Check the latest studies of Hyrimoz.

On Jul, 14, 2026

64 people who take Naproxen and Hyrimoz together, and have interactions are studied.

What are the common drug interactions of Naproxen and Hyrimoz, by gender? *:

female:

Hypokalaemia (low potassium)
Hypotension (abnormally low blood pressure)
Immunodeficiency
Juvenile idiopathic arthritis (a subset of arthritis seen in childhood)
Loss of consciousness
Pleural effusion (water on the lungs)
Polyarthritis (arthritis which involves 5 or more joints simultaneously)
Red blood cell sedimentation rate increased
Septic shock (shock due to blood infection)
Insomnia (sleeplessness)

male:

Arthralgia (joint pain)
Abdominal pain
Chest pain
Drug intolerance (drug sensitivity)
Dyspnoea (difficult or laboured respiration)
Eye disorder
Hypersensitivity
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting
Discomfort

What are the common drug interactions of Naproxen and Hyrimoz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Antibody test positive
Bone density decreased
C-reactive protein increased
Diarrhoea
Dizziness
Drug ineffective
Drug intolerance (drug sensitivity)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)

10-19:

Body temperature increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Drug ineffective
Fatigue (feeling of tiredness)
Ill-defined disorder
Insomnia (sleeplessness)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Thirst
Vertigo

20-29:

Ankylosing spondylitis (type of arthritis affecting the spine)
Asthenia (weakness)
Fatigue (feeling of tiredness)
Feeling hot
Influenza like illness
Muscular weakness (muscle weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Rhinorrhoea (watery mucus discharge from the nose)

30-39:

Abdominal discomfort
Ankylosing spondylitis (type of arthritis affecting the spine)
Drug ineffective
Inflammation
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Spinal pain (pain in spine)
White blood cells stool positive
Abscess limb (limb infection)
Adverse drug reaction
Fatigue (feeling of tiredness)

40-49:

Gastrointestinal disorder (functional problems of gastrointestinal tract)
Anti-cyclic citrullinated peptide antibody positive
Confusional state
Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
Fatigue (feeling of tiredness)
Folliculitis (infection of hair root)
Glossodynia (a burning or painful sensation in the tongue)
Hand deformity
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Infection

50-59:

Discomfort
Joint swelling
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Ankylosing spondylitis (type of arthritis affecting the spine)
Drug ineffective
Enthesopathy (disorder of entheses (bone attachments))
General physical health deterioration (weak health status)
Neck pain
Psoriasis (immune-mediated disease that affects the skin)
Rash

60+:

Drug ineffective
Arthralgia (joint pain)
Chest pain
Eye swelling
Gait disturbance
Hypersensitivity
Kidney infection
Ocular hyperaemia (an abnormally large amount of blood in eye)
Pulmonary oedema (fluid accumulation in the lungs)
Thirst

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 27 people, 42.19%
Ankylosing Spondylitis (type of arthritis affecting the spine): 19 people, 29.69%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 10 people, 15.62%
Psoriasis (immune-mediated disease that affects the skin): 9 people, 14.06%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 12.50%
Seasonal Allergy (allergic condition due to certain season): 7 people, 10.94%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 7 people, 10.94%
Drowsiness: 7 people, 10.94%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 10.94%
Allergic Rhinitis: 6 people, 9.38%

* Approximation only. Some reports may have incomplete information.

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