Norvasc and Lacosamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norvasc (amlodipine besylate) and Lacosamide (lacosamide). Common drug interactions include cognitive disorder among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Norvasc and Lacosamide. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Norvasc?

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 136,738 Norvasc users. Check the latest studies of Norvasc.

What is Lacosamide?

Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.



On Jul, 11, 2026

37 people who take Norvasc and Lacosamide together, and have interactions are studied.

Norvasc and Lacosamide drug interactions.

What are the common drug interactions of Norvasc and Lacosamide, by gender? *:

female:

  1. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  2. Constipation
  3. Deformity (disfigurement)
  4. Delusion (a false belief or opinion)
  5. Depression
  6. Diplopia (double vision)
  7. Dizziness
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Dysstasia (difficulty in standing)
  10. Embolic stroke (stroke due to obstruction due to an embolus)

male:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Drug ineffective
  3. Partial seizures (seizures which affect only a part of the brain at onset)
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Tremor (trembling or shaking movements in one or more parts of your body)
  8. Cough
  9. Gastritis haemorrhagic (inflammation of stomach with bleeding)
  10. Lethargy (tiredness)

What are the common drug interactions of Norvasc and Lacosamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Migraine (headache)
  2. Agraphia (a loss of the ability to write or to express thoughts in writing because of a brain lesion)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Brain injury
  5. Cerebral artery thrombosis (clot formation in brain blood vessels)
  6. Cerebral haemorrhage (bleeding within the brain)
  7. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  8. Deformity (disfigurement)
  9. Depression
  10. Diplopia (double vision)

50-59:

  1. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  2. Partial seizures (seizures which affect only a part of the brain at onset)
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Asthenia (weakness)
  5. Brain neoplasm malignant (brain cancer tumour)
  6. Drug ineffective
  7. Essential hypertension (primary hypertension)
  8. Gait disturbance
  9. Nystagmus (a condition of involuntary eye movement)
  10. Overdose

60+:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Death
  3. Respiratory failure (inadequate gas exchange by the respiratory system)
  4. Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  5. Drug ineffective
  6. Fatigue (feeling of tiredness)
  7. Gastritis haemorrhagic (inflammation of stomach with bleeding)
  8. Renal impairment (severely reduced kidney function)
  9. Arthralgia (joint pain)
  10. Back pain

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 19 people, 51.35%
  2. Constipation: 4 people, 10.81%
  3. Headache (pain in head): 4 people, 10.81%
  4. Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 4 people, 10.81%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.81%
  6. Hemiparesis (weakness on one side of the body): 3 people, 8.11%
  7. Fatigue (feeling of tiredness): 3 people, 8.11%
  8. Partial Seizures With Secondary Generalisation (partial seizure may spread within the brain, a process known as secondary generalization): 3 people, 8.11%
  9. Partial Seizures (seizures which affect only a part of the brain at onset): 3 people, 8.11%
  10. Movement - Uncoordinated: 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

Do you take Norvasc and Lacosamide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Norvasc and Lacosamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norvasc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lacosamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Norvasc and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lacosamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate and lacosamide (the active ingredients of Norvasc and Lacosamide, respectively), and Norvasc and Lacosamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: