Probenecid and Amlodipine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Probenecid (probenecid) and Amlodipine (amlodipine besylate). Common drug interactions include aplastic anaemia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Probenecid and Amlodipine. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Probenecid?

Probenecid has active ingredients of probenecid. It is often used in gout. eHealthMe is studying from 560 Probenecid users. Check the latest studies of Probenecid.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

On Jul, 20, 2026

25 people who take Probenecid and Amlodipine together, and have interactions are studied.

Probenecid and Amlodipine drug interactions.

What are the common drug interactions of Probenecid and Amlodipine, by gender? *:

female:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Chronic kidney disease
Death
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Pneumonia
Renal failure (kidney dysfunction)

male:

Pneumonia
Anxiety
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dizziness
Fluid overload (too much fluid in the blood)
Haematocrit decreased
Hyperkalaemia (damage to or disease of the kidney)
Loss of consciousness
Malignant hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage)

What are the common drug interactions of Probenecid and Amlodipine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Injection site pain
Oxygen saturation decreased
Productive cough
Pyrexia (fever)
Respiratory tract congestion (blockage on respiratory system)
Blood testosterone decreased
Disease recurrence
Drug ineffective
Hypoglycaemia (deficiency of glucose in the bloodstream)
Lyme disease (a bacterial infection that is spread to humans by infected ticks)

60+:

Dyspepsia (indigestion)
Pneumonia
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dizziness
Fluid overload (too much fluid in the blood)
Haematocrit decreased
Hyperkalaemia (damage to or disease of the kidney)
Loss of consciousness
Malignant hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

What are the existing conditions these people have? *

Depression: 7 people, 28.00%
Pain: 5 people, 20.00%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 16.00%
High Blood Cholesterol: 4 people, 16.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.00%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 12.00%
Lyme Disease (a bacterial infection that is spread to humans by infected ticks): 3 people, 12.00%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 12.00%
Thyroid Diseases: 2 people, 8.00%
Stress And Anxiety: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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