Provocholine and Naproxen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Provocholine (methacholine chloride) and Naproxen (naproxen). Common drug interactions include gingival pain among females and angiofibroma among males.
The phase IV clinical study analyzes what interactions people have when they take Provocholine and Naproxen. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Provocholine?
Provocholine has active ingredients of methacholine chloride. eHealthMe is studying from 80 Provocholine users. Check the latest studies of Provocholine.
What is Naproxen?
Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.
23 people who take Provocholine and Naproxen together, and have interactions are studied.

What are the common drug interactions of Provocholine and Naproxen, by gender? *:
female:
- Gingival pain (gum pain)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
- Impaired healing
- Ingrowing nail
- Injury
- Intervertebral disc protrusion (spinal disc protrusion)
- Lumbar radiculopathy (radicular pain in the low back and legs)
- Metastases to bone (cancer spreads to bone)
male:
- Angiofibroma (small, reddish brown or even flesh-coloured, smooth, shiny, 0.1- to 0.3 cm papules present over the sides of the nose and the medial portions of the cheeks)
- Anxiety
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cellulitis (infection under the skin)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Compression fracture (fracture due to pressure caused by injury)
- Contusion (a type of hematoma of tissue in which capillaries)
- Craniocerebral injury (injury to cranium and brain)
- Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
- Discomfort
What are the common drug interactions of Provocholine and Naproxen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Anxiety
- Areflexia (absence of a reflex)
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
- Impaired healing
- Ingrowing nail
- Injury
- Intervertebral disc protrusion (spinal disc protrusion)
- Lumbar radiculopathy (radicular pain in the low back and legs)
- Metastases to bone (cancer spreads to bone)
- Mitral valve prolapse (heart's mitral valve doesn't work well)
60+:
n/a
What are the existing conditions these people have? *
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 23 people, 100.00%
- Breast Cancer: 23 people, 100.00%
- Breast Cancer Metastatic: 22 people, 95.65%
* Approximation only. Some reports may have incomplete information.
Do you take Provocholine and Naproxen?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Provocholine (80 reports)
- Naproxen (72,032 reports)
Browse all drug interactions of Provocholine and Naproxen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Provocholine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Naproxen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Provocholine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Naproxen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on methacholine chloride and naproxen (the active ingredients of Provocholine and Naproxen, respectively), and Provocholine and Naproxen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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