Ritalin and Ramipril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ritalin (methylphenidate hydrochloride) and Ramipril (ramipril). Common drug interactions include pancreatitis among females and surgery among males.

The phase IV clinical study analyzes what interactions people have when they take Ritalin and Ramipril. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

What is Ramipril?

Ramipril has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 147,397 Ramipril users. Check the latest studies of Ramipril.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

80 people who take Ritalin and Ramipril together, and have interactions are studied.

What are the common drug interactions of Ritalin and Ramipril, by gender? *:

female:

Pancreatitis (inflammation of pancreas)
Rotator cuff repair
Somnolence (a state of near-sleep, a strong desire for sleep)
Acute myocardial infarction (acute heart attack)
Arthropathy
Blood pressure fluctuation
Blood sodium decreased
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Cardiac failure congestive
Chest pain

male:

Surgery
Fall
Spinal stenosis (narrowing of spinal column)
Anaemia postoperative
Asthma
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Diarrhoea
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Osteopenia (a condition where bone mineral density is lower than normal)
Varicose vein (veins that have become enlarged and tortuous)

What are the common drug interactions of Ritalin and Ramipril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Dizziness
Headache (pain in head)
Tinnitus (a ringing in the ears)
Vomiting
Anaemia (lack of blood)
Diarrhoea
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Haemorrhage (bleeding)

20-29:

Acute myocardial infarction (acute heart attack)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Chest pain
Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder disorder

30-39:

n/a

40-49:

Chest pain
Congestive cardiomyopathy (weakening of heart muscle)
Cough
Dyspnoea (difficult or laboured respiration)
Exercise tolerance decreased
Fatigue (feeling of tiredness)
Rebound effect (take-back effect)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

50-59:

Drug ineffective
Drug hypersensitivity
Gastric disorder (disease of stomach)
Muscle spasms (muscle contraction)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Surgery
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Pain
Death
Fluid retention (an abnormal accumulation of fluid in the blood)

60+:

Surgery
Anaemia postoperative
Somnolence (a state of near-sleep, a strong desire for sleep)
Alopecia (absence of hair from areas of the body)
Anaphylactic reaction (serious allergic reaction)
Blood cholesterol increased
Blood pressure fluctuation
Blood sodium decreased
Cardiac arrest
Colorectal cancer (colon cancer or bowel cancer)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 45 people, 56.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 31 people, 38.75%
High Blood Cholesterol: 9 people, 11.25%
Bipolar Disorder (mood disorder): 9 people, 11.25%
Drowsiness: 7 people, 8.75%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 7.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.50%
Depression: 6 people, 7.50%
Stress And Anxiety: 4 people, 5.00%
Pain: 4 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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