Sulfamethoxazole and Reyataz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sulfamethoxazole (sulfamethoxazole) and Reyataz (atazanavir sulfate). Common drug interactions include fibula fracture among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Sulfamethoxazole and Reyataz. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Sulfamethoxazole?

Sulfamethoxazole has active ingredients of sulfamethoxazole. It is often used in urinary tract infection. eHealthMe is studying from 13,360 Sulfamethoxazole users. Check the latest studies of Sulfamethoxazole.

What is Reyataz?

Reyataz has active ingredients of atazanavir sulfate. It is often used in hiv infection. eHealthMe is studying from 11,386 Reyataz users. Check the latest studies of Reyataz.



On Jul, 13, 2026

75 people who take Sulfamethoxazole and Reyataz together, and have interactions are studied.

Sulfamethoxazole and Reyataz drug interactions.

What are the common drug interactions of Sulfamethoxazole and Reyataz, by gender? *:

female:

  1. Fibula fracture
  2. Multiple fractures
  3. Spinal fracture (fracture in one of vertebrae)
  4. Tibia fracture (fracture of lower leg bone)
  5. Gait disturbance
  6. Bone loss
  7. Femur fracture
  8. Osteonecrosis (death of bone)
  9. Tooth loss
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Anxiety
  2. Emotional distress
  3. Osteonecrosis (death of bone)
  4. Renal impairment (severely reduced kidney function)
  5. Bone loss
  6. Multiple fractures
  7. Spinal compression fracture (fracture due to spinal compression on bone)
  8. Gait disturbance
  9. Back pain
  10. Decreased activity

What are the common drug interactions of Sulfamethoxazole and Reyataz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Pain
  5. Bone density decreased
  6. Chronic kidney disease
  7. Fatigue (feeling of tiredness)
  8. Anaemia (lack of blood)
  9. Asthenia (weakness)
  10. Calcinosis (calcium deposits in any soft tissue)

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Pain
  5. Depression
  6. Chronic kidney disease
  7. Bone density decreased
  8. Dyspnoea (difficult or laboured respiration)
  9. Renal failure (kidney dysfunction)
  10. Back pain

40-49:

  1. Dysuria (painful or difficult urination)
  2. Facial bones fracture (bone fracture of face)
  3. Fall
  4. Gait disturbance
  5. Humerus fracture (injury to the upper arm bone)
  6. Hypokinesia (decreased bodily movement)
  7. Loose tooth
  8. Mobility decreased (ability to move is reduced)
  9. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint)

50-59:

  1. Chronic kidney disease
  2. Emotional distress
  3. Pain
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Anxiety
  6. Osteoporosis (bones weak and more likely to break)
  7. Bone density decreased
  8. Osteopenia (a condition where bone mineral density is lower than normal)
  9. Bone loss
  10. Fibula fracture

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Spinal compression fracture (fracture due to spinal compression on bone)
  4. Gait disturbance
  5. Depression
  6. Dyspnoea (difficult or laboured respiration)
  7. Arthralgia (joint pain)
  8. Back pain
  9. Clavicle fracture
  10. Jaw fracture

What are the existing conditions these people have? *

  1. Hiv Infection: 71 people, 94.67%
  2. Pain: 13 people, 17.33%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 13.33%
  4. Bacterial Infection: 9 people, 12.00%
  5. Nausea (feeling of having an urge to vomit): 8 people, 10.67%
  6. Infection: 8 people, 10.67%
  7. High Blood Pressure: 8 people, 10.67%
  8. Hypersensitivity: 7 people, 9.33%
  9. Inflammation: 6 people, 8.00%
  10. Cough: 6 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Sulfamethoxazole and Reyataz?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sulfamethoxazole and Reyataz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sulfamethoxazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Reyataz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sulfamethoxazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Reyataz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole and atazanavir sulfate (the active ingredients of Sulfamethoxazole and Reyataz, respectively), and Sulfamethoxazole and Reyataz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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