A study for a 50 year old woman who takes Wellbutrin Xl, Topamax, Wellbutrin, Suboxone, Celebrex, Wegovy, Lexapro (an AI-powered real world drug study)
Summary:
18 females aged 50 (±5) who take the same drugs and have adverse effects are studied. This is a phase IV clinical study for a 50 year old female patient who has Generalised Anxiety Disorder, Migraine, Chronic Back Pain, Arthritis, Lose Weight, Major Depression. The study is created by eHealthMe based on reports from sources including the FDA.
18 females aged 50 (±5) who take Wellbutrin Xl, Topamax, Wellbutrin, Suboxone, Celebrex, Wegovy, Lexapro and have adverse effects are studied.
Number of reports submitted per year:

Information of the patient in this study:
- Age: 50
- Gender: female
What are the drugs?
- Wellbutrin xl has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 22,999 Wellbutrin xl users. Check the latest studies of Wellbutrin xl.
- Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,955 Topamax users. Check the latest studies of Topamax.
- Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 117,110 Wellbutrin users. Check the latest studies of Wellbutrin.
- Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 31,249 Suboxone users. Check the latest studies of Suboxone.
- Celebrex has active ingredients of celecoxib. It is often used in arthritis. eHealthMe is studying from 151,105 Celebrex users. Check the latest studies of Celebrex.
- Wegovy has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 4,886 Wegovy users. Check the latest studies of Wegovy.
- Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.
What are the conditions?
- Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry) is found to be associated with 1,163 drugs and 1,595 conditions by eHealthMe. Check the latest studies of Generalised anxiety disorder.
- Migraine (headache) is found to be associated with 2,051 drugs and 2,351 conditions by eHealthMe. Check the latest studies of Migraine.
- Chronic back pain is found to be associated with 1 condition by eHealthMe. Check the latest studies of Chronic back pain.
- Arthritis (form of joint disorder that involves inflammation of one or more joints) is found to be associated with 1,963 drugs and 2,259 conditions by eHealthMe. Check the latest studies of Arthritis.
- Lose weight is found to be associated with 2,434 drugs and 2,390 conditions by eHealthMe. Check the latest studies of Lose weight.
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings) is found to be associated with 800 drugs and 1,477 conditions by eHealthMe. Check the latest studies of Major depression.
What are the adverse effects?
- Blood insulin decreased is found to be associated with 29 drugs and 64 conditions by eHealthMe. Check the latest studies of Blood insulin decreased.
- Heart pounding or racing (feelings or sensations that your heart is pounding or racing) is found to be associated with 3,771 drugs and 3,809 conditions by eHealthMe. Check the latest studies of Heart pounding or racing.
Comparison with patient's specific adverse outcomes:
You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.
By the same drug(s):
-
Blood Insulin Decreased:
- among females aged 50 (±5) who take the same drugs: 0% (0 of 18)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 89) -
Heart Pounding Or Racing (feelings or sensations that your heart is pounding or racing):
- among females aged 50 (±5) who take the same drugs: 0% (0 of 18)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 89)
By each condition:
-
people who have Blood Insulin Decreased with Major Depression:
- among females aged 50 (±5) who have Major Depression: 0% (0 of 3,382)
- among people who have Major Depression, regardless of gender or age: 0% (0 of 31,832) -
people who have Blood Insulin Decreased with Lose Weight:
- among females aged 50 (±5) who have Lose Weight: 0.03% (1 of 3,471)
- among people who have Lose Weight, regardless of gender or age: 0.03% (7 of 23,430) -
people who have Blood Insulin Decreased with Generalised Anxiety Disorder:
- among females aged 50 (±5) who have Generalised Anxiety Disorder: 0% (0 of 1,250)
- among people who have Generalised Anxiety Disorder, regardless of gender or age: 0% (0 of 13,638) -
people who have Blood Insulin Decreased with Migraine:
- among females aged 50 (±5) who have Migraine: 0% (0 of 20,269)
- among people who have Migraine, regardless of gender or age: 0% (0 of 135,537) -
people who have Blood Insulin Decreased with Chronic Back Pain:
- among females aged 50 (±5) who have Chronic Back Pain: 0% (0 of 2)
- among people who have Chronic Back Pain, regardless of gender or age: 0% (0 of 18) -
people who have Blood Insulin Decreased with Arthritis:
- among females aged 50 (±5) who have Arthritis: 0% (0 of 7,171)
- among people who have Arthritis, regardless of gender or age: 0% (0 of 90,309) -
people who have Heart Pounding Or Racing with Major Depression:
- among females aged 50 (±5) who have Major Depression: 1.98% (67 of 3,382)
- among people who have Major Depression, regardless of gender or age: 1% (319 of 31,832) -
people who have Heart Pounding Or Racing with Lose Weight:
- among females aged 50 (±5) who have Lose Weight: 2.07% (72 of 3,471)
- among people who have Lose Weight, regardless of gender or age: 1.68% (394 of 23,430) -
people who have Heart Pounding Or Racing with Generalised Anxiety Disorder:
- among females aged 50 (±5) who have Generalised Anxiety Disorder: 1.84% (23 of 1,250)
- among people who have Generalised Anxiety Disorder, regardless of gender or age: 2.05% (280 of 13,638) -
people who have Heart Pounding Or Racing with Migraine:
- among females aged 50 (±5) who have Migraine: 1.46% (296 of 20,269)
- among people who have Migraine, regardless of gender or age: 1.19% (1,611 of 135,537) -
people who have Heart Pounding Or Racing with Chronic Back Pain:
- among females aged 50 (±5) who have Chronic Back Pain: 0% (0 of 2)
- among people who have Chronic Back Pain, regardless of gender or age: 0% (0 of 18) -
people who have Heart Pounding Or Racing with Arthritis:
- among females aged 50 (±5) who have Arthritis: 1.52% (109 of 7,171)
- among people who have Arthritis, regardless of gender or age: 0.98% (883 of 90,309)
By each drug (FDA data only):
-
people who take Lexapro and have Blood Insulin Decreased:
- among females aged 50 (±5) who take Lexapro and have side effects: 0% (0 of 9,722)
- among people who take Lexapro and have side effects, regardless of gender or age: 0% (1 of 82,253) -
people who take Wellbutrin Xl and have Blood Insulin Decreased:
- among females aged 50 (±5) who take Wellbutrin Xl and have side effects: 0% (0 of 2,273)
- among people who take Wellbutrin Xl and have side effects, regardless of gender or age: 0% (0 of 18,205) -
people who take Topamax and have Blood Insulin Decreased:
- among females aged 50 (±5) who take Topamax and have side effects: 0% (0 of 7,625)
- among people who take Topamax and have side effects, regardless of gender or age: 0% (0 of 54,173) -
people who take Suboxone and have Blood Insulin Decreased:
- among females aged 50 (±5) who take Suboxone and have side effects: 0% (0 of 1,565)
- among people who take Suboxone and have side effects, regardless of gender or age: 0% (0 of 28,312) -
people who take Celebrex and have Blood Insulin Decreased:
- among females aged 50 (±5) who take Celebrex and have side effects: 0% (0 of 14,459)
- among people who take Celebrex and have side effects, regardless of gender or age: 0% (0 of 147,580) -
people who take Wegovy and have Blood Insulin Decreased:
- among females aged 50 (±5) who take Wegovy and have side effects: 0% (0 of 560)
- among people who take Wegovy and have side effects, regardless of gender or age: 0.02% (1 of 4,836) -
people who take Wellbutrin and have Blood Insulin Decreased:
- among females aged 50 (±5) who take Wellbutrin and have side effects: 0% (0 of 13,356)
- among people who take Wellbutrin and have side effects, regardless of gender or age: 0% (1 of 101,604) -
people who take Suboxone and have Heart Pounding Or Racing:
- among females aged 50 (±5) who take Suboxone and have side effects: 2.11% (33 of 1,565)
- among people who take Suboxone and have side effects, regardless of gender or age: 0.7% (197 of 28,312) -
people who take Celebrex and have Heart Pounding Or Racing:
- among females aged 50 (±5) who take Celebrex and have side effects: 1.72% (248 of 14,459)
- among people who take Celebrex and have side effects, regardless of gender or age: 1.04% (1,538 of 147,580) -
people who take Wegovy and have Heart Pounding Or Racing:
- among females aged 50 (±5) who take Wegovy and have side effects: 1.96% (11 of 560)
- among people who take Wegovy and have side effects, regardless of gender or age: 1.03% (50 of 4,836) -
people who take Wellbutrin and have Heart Pounding Or Racing:
- among females aged 50 (±5) who take Wellbutrin and have side effects: 1.91% (255 of 13,356)
- among people who take Wellbutrin and have side effects, regardless of gender or age: 1.21% (1,232 of 101,604) -
people who take Lexapro and have Heart Pounding Or Racing:
- among females aged 50 (±5) who take Lexapro and have side effects: 1.94% (189 of 9,722)
- among people who take Lexapro and have side effects, regardless of gender or age: 1.36% (1,115 of 82,253) -
people who take Wellbutrin Xl and have Heart Pounding Or Racing:
- among females aged 50 (±5) who take Wellbutrin Xl and have side effects: 2.29% (52 of 2,273)
- among people who take Wellbutrin Xl and have side effects, regardless of gender or age: 1.57% (285 of 18,205) -
people who take Topamax and have Heart Pounding Or Racing:
- among females aged 50 (±5) who take Topamax and have side effects: 1.27% (97 of 7,625)
- among people who take Topamax and have side effects, regardless of gender or age: 1.08% (587 of 54,173)
Common drug interactions *:
- Back Pain : 6 people, 33.33%
- Cervical Spinal Stenosis (narrowing of the spinal canal in the neck): 5 people, 27.78%
- General Physical Health Deterioration (weak health status): 5 people, 27.78%
- Drug Ineffective : 5 people, 27.78%
- Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 5 people, 27.78%
- Suicidal Ideation : 5 people, 27.78%
- Intervertebral Disc Protrusion (spinal disc protrusion): 5 people, 27.78%
- Muscle Aches (muscle pain): 5 people, 27.78%
- Borderline Personality Disorder : 4 people, 22.22%
- Chronic Kidney Disease : 4 people, 22.22%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 16.67%
- High Blood Pressure : 2 people, 11.11%
- Disability : 2 people, 11.11%
- Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 11.11%
- Osteoporosis (bones weak and more likely to break): 2 people, 11.11%
- Clavicle Fracture : 2 people, 11.11%
- Diabetes : 2 people, 11.11%
- Foot Fracture : 2 people, 11.11%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.11%
- Emotional Disorder : 1 person, 5.56%
Common co-existing conditions *:
You may use this to check any potential undetected conditions.
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 61.11%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 38.89%
- Hypersensitivity : 5 people, 27.78%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 27.78%
- Insomnia (sleeplessness): 4 people, 22.22%
- Infection : 3 people, 16.67%
- High Blood Cholesterol : 3 people, 16.67%
- Inflammation : 3 people, 16.67%
- Bipolar Disorder (mood disorder): 3 people, 16.67%
- Diabetes : 2 people, 11.11%
- Cough : 2 people, 11.11%
- Constipation : 2 people, 11.11%
- Headache (pain in head): 2 people, 11.11%
- Bone Disorder : 2 people, 11.11%
- Hypokalemia (low potassium): 2 people, 11.11%
- Immune System Disorder : 2 people, 11.11%
- Back Pain : 2 people, 11.11%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 11.11%
- Affective Disorder (mental disorder): 2 people, 11.11%
- Sleep Apnea Syndrome : 2 people, 11.11%
Common co-used drugs *:
You may use this to check any potential interacting drugs.
- Abilify (12 people, 66.67%)
- Lyrica (10 people, 55.56%)
- Xyrem (10 people, 55.56%)
- Synthroid (10 people, 55.56%)
- Valium (10 people, 55.56%)
- Savella (9 people, 50.00%)
- Depakote (8 people, 44.44%)
- Nucynta (8 people, 44.44%)
- Zantac (8 people, 44.44%)
- Seroquel (8 people, 44.44%)
- Amitiza (8 people, 44.44%)
- Viibryd (8 people, 44.44%)
- Robaxin (7 people, 38.89%)
- Dilaudid (7 people, 38.89%)
- Elmiron (7 people, 38.89%)
- Vivelle-Dot (7 people, 38.89%)
- Vagifem (7 people, 38.89%)
- Inderal (6 people, 33.33%)
- Cymbalta (6 people, 33.33%)
- Opana (6 people, 33.33%)
Drug effectiveness *:
Wellbutrin Xl:
n/a
Topamax:
n/a
Wellbutrin:
n/a
Suboxone:
n/a
Celebrex:
n/a
Wegovy:
n/a
Lexapro:
n/a
* Some reports may have incomplete information.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related studies
Drug side effects in long term, by gender and age:
- Celebrex: 151,105 reports
- Lexapro: 91,464 reports
- Suboxone: 31,249 reports
- Topamax: 58,955 reports
- Wegovy: 4,886 reports
- Wellbutrin: 117,110 reports
- Wellbutrin xl: 22,999 reports
Treatments, associated medications and conditions:
- Arthritis: 188,668 reports
- Blood insulin decreased: 241 reports
- Chronic back pain: 708 reports
- Generalised anxiety disorder: 31,280 reports
- Heart pounding or racing: 147,650 reports
- Lose weight: 62,431 reports
- Major depression: 44,981 reports
- Migraine: 234,064 reports
Drug side effects:
- Wellbutrin xl and Blood insulin decreased
- Topamax and Blood insulin decreased
- Wellbutrin and Blood insulin decreased
- Suboxone and Blood insulin decreased
- Celebrex and Blood insulin decreased
- Wegovy and Blood insulin decreased
- Lexapro and Blood insulin decreased
- Wellbutrin xl and Heart pounding or racing (285 reports)
- Topamax and Heart pounding or racing (587 reports)
- Wellbutrin and Heart pounding or racing (1,232 reports)
- Suboxone and Heart pounding or racing (197 reports)
- Celebrex and Heart pounding or racing (1,538 reports)
- Wegovy and Heart pounding or racing (50 reports)
- Lexapro and Heart pounding or racing (1,115 reports)
Drug interactions:
- Wellbutrin xl and Topamax drug interaction (533 reports)
- Wellbutrin xl and Wellbutrin drug interaction
- Wellbutrin xl and Suboxone drug interaction (56 reports)
- Wellbutrin xl and Celebrex drug interaction (373 reports)
- Wellbutrin xl and Wegovy drug interaction (6 reports)
- Wellbutrin xl and Lexapro drug interaction (1,041 reports)
- Topamax and Wellbutrin drug interaction (3,514 reports)
- Topamax and Suboxone drug interaction (166 reports)
- Topamax and Celebrex drug interaction (1,632 reports)
- Topamax and Wegovy drug interaction (9 reports)
- Topamax and Lexapro drug interaction (2,512 reports)
- Wellbutrin and Suboxone drug interaction (434 reports)
- Wellbutrin and Celebrex drug interaction (3,114 reports)
- Wellbutrin and Wegovy drug interaction (37 reports)
- Wellbutrin and Lexapro drug interaction (6,197 reports)
- Suboxone and Celebrex drug interaction (132 reports)
- Suboxone and Wegovy drug interaction
- Suboxone and Lexapro drug interaction (281 reports)
- Celebrex and Wegovy drug interaction (6 reports)
- Celebrex and Lexapro drug interaction (2,254 reports)
- Wegovy and Lexapro drug interaction (23 reports)
Symptoms:
- Generalised anxiety disorder and Blood insulin decreased
- Generalised anxiety disorder and Heart pounding or racing (280 reports)
- Migraine and Blood insulin decreased
- Migraine and Heart pounding or racing (1,611 reports)
- Chronic back pain and Blood insulin decreased
- Chronic back pain and Heart pounding or racing
- Arthritis and Blood insulin decreased
- Arthritis and Heart pounding or racing (883 reports)
- Lose weight and Blood insulin decreased
- Lose weight and Heart pounding or racing (394 reports)
- Major depression and Blood insulin decreased
- Major depression and Heart pounding or racing (319 reports)
Drugs that are associated with:
- Blood insulin decreased: 29 drugs
- Heart pounding or racing: 3,771 drugs
Conditions that are associated with:
- Blood insulin decreased: 64 conditions
- Heart pounding or racing: 3,809 conditions
How the phase IV clinical study uses the data?
The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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